The potential of lipocalin-2/NGAL as biomarker for inflammatory and metabolic diseases

Figures & data

Figure 1. Schematic representation of the main functions of lipocalin-2.

Table 1. Potential value of LCN2 as a biomarker in several diseases.

Biomarker	Disease	Reference
Plasma LCN2	Arthritic diseases	Wilson et al. (2008)
Plasma LCN2	Severe acute pancreatitis	Chakraborty et al. (2012)
Plasma LCN2	Obesity-related metabolic	Jang et al. (2012)
Plasma LCN2	Cardiovascular disease	Lindberg et al. (2014)
Urinary LCN2	Acute kidney injury	Bolignano et al. (2008)
Urinary LCN2	Lupus nephritis	Brunner et al. (2012)
Fecal LCN2	Intestinal inflammation	Chassaing et al. (2012)
Plasma LCN2	Multiple sclerosis	Berard et al. (2012)

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Berard JL, Zarruk JG, Arbour N, et al. (2012). Lipocalin 2 is a novel immune mediator of experimental autoimmune encephalomyelitis pathogenesis and is modulated in multiple sclerosis. Glia 60:1145–59

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