The high prevalence of testosterone deficiency in population of Polish men over 65 years with erectile dysfunctions

Figures & data

Table I.  Mean hormones levels and percentage of patients in five cutpoints of testosterone levels in men with erectile dysfunction.

	Testosterone levels
	<200 ng/dL	<250 ng/dL	<300 ng/dL	<350 ng/dL	>350 ng/dL
Number of patients (%)	49 (17)	95 (33)	124 (42)	164 (57)	122 (43)
Testosterone (ng/dL)	184 ± 12	235 ± 11	283 ± 9	331 ± 15	438 ± 24
LH (IU/L)	7.1 ± 0.7	6.4 ± 0.6	6.2 ± 0.3	6.3 ± 0.9	5.9 ± 1.6
FSH (IU/L)	7.2 ± 1.2	7.0 ± 0.9	6.7 ± 0.9	7.4 ± 0.6	6.8 ± 1.2
Prolactin (ng/mL)	12 ± 2.7	11.4 ± 3.6	14.6 ± 2.8	13.4 ± 3.1	12.7 ± 2.9

FSH, follicle-stimulating hormone; LH, luteinizing hormone.

Table II.  Serum testosterone concentration in four age groups.

Years	Number of patients	Testosterone (ng/dL)
<65	75	489 ± 161*
65–70	83	411 ± 179
70–75	66	356 ± 156
>75	62	321 ± 162

*p < 0.05 among all groups, except <65 years and 65–70 years group.

Pearson coefficients of age and total testosterone p < 0.05; r = –0.3328.

Table III.  Degree of erectile dysfunction according to IIEF-5 scale in all group and in different ages.

	IIEF-5 (Number of patients, %)
	Number of patients	Mild	Mild-to-moderate	Moderate	Severe
<65 years	75	41 (54.7)	18 (24)	9 (12)	7 (9.3)
65–70 years	83	35 (42.2)	23 (27.7)	14 (16.8)	11 (13.3)
70–75 years	66	24 (36,4)	20 (30.3)	13 (19.7)	9 (13.6)
>75 years	62	13 (21)	14 (22.6)	16 (25.8)	19 (30.6)
Total	286	113 (39.5)	75 (26.2)	52 (18.2)	46 (16.0)

Significant differences between group <65 years of age and >75 years of age (p < 0.02).

Variables of IIEF-5 score and age: r = –0.3463, p < 0.05.

Figure 1.  The prevalence (%) of low and low-normal testosterone concentration in men with erectile dysfunctions in population of Polish men over 65 years of age.

Table IV.  Clinical characteristic of patients with ED in all group and in five cutpoints of testosterone levels.

	All groupNumber of patients (%)	Testosterone concentration
		<200 ng/dL	<250 ng/dL	<300 ng/dL	<350 ng/dL	>350 ng/dL
Number of patients (%)	286 (100)	49 (17)	95 (33)	124 (42)	164 (57)	122 (43)	p
Obesity	232 (81)	43 (88)	89 (90)	101 (81)	149 (91)	83 (68)	0.001
Current smoker	28 (45)	36 (73)	73 (77)	89 (72)	69 (69)	59 (48)	0.001
Hypertension	198 (69)	41 (84)	78 (81)	103 (83)	120 (73)	78 (64)	0.02
Dyslipidemia	222 (78)	45 (92)	85 (89)	109 (88)	156 (95)	66 (54)	0.001
CVD	177 (62)	36 (73)	56 (60)	70 (56)	121 (74)	56 (46)	0.001
IFG	184 (64)	29 (59)	62 (65)	74 (59)	131 (80)	53 (43)	0.001

p shows significant differences between patients with testosterone levels <350 ng/dL compared with patients with testosterone levels >350 ng/mL.

CVD, cardiovascular disease; ED, erectile dysfunction; IFG, impaired fasting glucose.