Evidence for low androgenicity among Indian (South Asian) men

Figures & data

Table 1. Basic demographic parameters of study subjects (mean ± SD).

Variable	Indian (n = 60)	White (n = 60)	Sig.
Age in years	64.28 ± 8.3	62.73 ± 8.1	0.304
Height (cm)	167.9 ± 5.9	177.3 ± 7.0	<0.001
Weight (kg)	70.99 ± 10.2	85.45 ± 14.7	<0.001
BMI (kg/m^2)	25.12 ± 2.9	27.15 ± 4.1	0.002

BMI: body mass index.

Table 2. Comparisons of hormone levels and number of CAG repeats between Indian and white Caucasian males (mean ± SD).

Values	Indian	White	Sig.
SHBG (nmol/L)	40.83 ± 16.4	45.40 ± 18.0	0.148
Free T (pmol/L)	17.3 ± 6.4	21.5 ± 11.2	0.014
Estradiol (pmol/L)	86.7 ± 21.6	94.7 ± 25.7	0.067
Estradiol/SHBG	2.44 ± 1.11	2.58 ± 1.68	0.585
#CAG repeats	22.30 ± 3.7	22.37 ± 3.1	0.916
Free testosterone/  estradiol/SHBG ratio	7.96 ± 3.69	9.70 ± 4.41	0.021

SHBG: sex hormone binding globulin, free T: free testosterone.

Table 3. Comparisons of skeletal muscle mass between Indian and white Caucasian males.

Skeletal muscle mass by region	Indian	White	Unadjusted Sig.	Adjusted Sig.*
Appendicular skeletal mass (kg)	20.70 ± 2.8	26.29 ± 3.5	<0.001	<0.001
Legs lean muscle (kg)	15.10 ± 2.0	19.22 ± 2.6	<0.001	<0.001
Arms lean muscle (kg)	5.60 ± 0.8	7.10 ± 1.0	<0.001	<0.001
Trunk lean muscle (kg)	21.81 ± 2.2	27.22 ± 3.9	<0.001	<0.001
Total body lean muscle (kg)	46.21 ± 4.9	57.63 ± 7.3	<0.001	<0.001

*Adjusted for BMI (body mass index).

Table 4. Comparisons of total and regional body fat in Indian and white Caucasian males.

Fat mass by region	Indian	White	T (df), sig	95%CI
Legs fat (kg)	6.05	6.87	−1.59 (118) p = 0.114	−1.84 to 0.20
Arms fat (kg)	1.84	1.98	−0.99 (118) p = 0.320	−0.43 to 0.14
Trunk fat (kg)^1	13.45	14.77	−1.45 (106) p = 0.151	−3.13 to 0.49
Total body  fat (kg)	22.10	24.36	−1.47 (118) p = 0.144	−5.31 to 0.79