Figures & data
Figure 1. In vitro radical scavenger activities of the methanol extract (▪) and ascorbic acid (○) on 1,1-diphenyl-1-picryl-hydrazyl (DPPH) free radical.
Figure 2. Concentration–response curves for relaxation induced by T. africanus extract on noradrenaline (NA) (♦) or KCl (•) precontrated aorta. The responses are expressed as % of maximum NA (10 μM) or KCl (30 mM) induced contraction. Values are mean ± SEM, n = 6.
Figure 3. Contractile concentration–response curves of guinea-pig aorta rings to cumulative addition of noradrenaline (NA) in the presence (•) or absence (□) of MeOH extract of T. africanus (300 μg/mL). Contraction is expressed as percentage of the maximal contraction (100%) induced by NA (10–4 M). Mean ± SEM, n = 6.
Figure 4. Contraction concentration–response curves of guinea-pig aorta rings to cumulative addition of KCl in the presence (•) or absence (□) of MeOH extract of T. africanus (300 μg/mL). Contraction is expressed as percentage of the maximal contraction (100%) induced by KCl (60 mM). Mean ± SEM, n = 6.
Figure 5. Vasorelaxant effect of MeOH extract of T. africanus-induced contractions of rat aorta rings with endothelium intact (♦) in the presence of indomethacin (10 μM, •) or l-NAME (100 μM, □). Mean ± SEM, n = 6.
Table 1. Effect of l-NAME and indomethacin on maximal relaxant responses and EC50 of the MeOH extract of T. africanus against NA-induced contractions.
Figure 6. Concentration–response curves for relaxation induced by MeOH extract of T. africanus (•) and nifedipine (□) on guinea-pig papillary muscle. Values are mean ± SEM, n = 6.
