Figures & data
Table 1. Effect of LEO or aspirin on writhing induced by acetic acid.
Table 2. Effect of LEO or aspirin on formalin-induced pain.
Table 3. Effect of LEO on the hot plate test in mice.
Figure 1. Effect of LEO on leukocyte migration into the peritoneal cavity induced by carrageenan in rats. Groups of rats were pre-treated with vehicle (C, control group, 10 mL/kg p.o., open column), dexamethasone (Dexa, 2 mg/kg s.c., cross-hatched column), or LEO in concentrations of 50, 100, and 200 mg/kg (p.o., right-hatched columns) 60 min before carrageenan-induced (500 µg/cavity, 500 µL i.p.) peritonitis. Cell counts were performed 4 h after the injection of carrageenan. Each value represents the mean ± SEM. Asterisks denote statistical significance, *p <0.001 related to control group. ANOVA followed by Tukey’s test (n = 6).
![Figure 1. Effect of LEO on leukocyte migration into the peritoneal cavity induced by carrageenan in rats. Groups of rats were pre-treated with vehicle (C, control group, 10 mL/kg p.o., open column), dexamethasone (Dexa, 2 mg/kg s.c., cross-hatched column), or LEO in concentrations of 50, 100, and 200 mg/kg (p.o., right-hatched columns) 60 min before carrageenan-induced (500 µg/cavity, 500 µL i.p.) peritonitis. Cell counts were performed 4 h after the injection of carrageenan. Each value represents the mean ± SEM. Asterisks denote statistical significance, *p <0.001 related to control group. ANOVA followed by Tukey’s test (n = 6).](/cms/asset/b540705a-ed0a-48d1-8af6-ebe544ebc642/iphb_a_428174_f0001_b.gif)
Figure 2. Kinetic behavior of the LEO determined spectrophotometrically at 515 nm by reaction with the methanol solution of DPPH (30 µg/mL).
![Figure 2. Kinetic behavior of the LEO determined spectrophotometrically at 515 nm by reaction with the methanol solution of DPPH (30 µg/mL).](/cms/asset/3fd05b61-544c-484e-887e-4ea566a19726/iphb_a_428174_f0002_b.gif)
Table 4. Radical scavenging activities of LEO determined by the reduction of DPPH free radical.