Figures & data
Figure 1. The antinociceptive effect of C. ovata extracts, morphine, dipyrone, and reversal effect of naloxone on tail-immersion test. Values are presented as the mean ± SEM (n = 6), (NLX; naloxone); aP < 0.001, significant difference from control; cP < 0.001, significant difference from morphine alone; fP < 0.01, significant difference from CME 200 mg/kg alone.
![Figure 1. The antinociceptive effect of C. ovata extracts, morphine, dipyrone, and reversal effect of naloxone on tail-immersion test. Values are presented as the mean ± SEM (n = 6), (NLX; naloxone); aP < 0.001, significant difference from control; cP < 0.001, significant difference from morphine alone; fP < 0.01, significant difference from CME 200 mg/kg alone.](/cms/asset/64919349-2938-4d3f-a5f6-a54f2db43dd6/iphb_a_463441_f0001_b.gif)
Figure 2. The antinociceptive effect of C. ovata extracts, morphine, dipyrone, and reversal effect of naloxone on the hot-plate test. Values are presented as the mean ± SEM (n = 6), (NLX; naloxone); aP < 0.001, significant difference from control; bP < 0.001, significant difference from dipyrone; cP < 0.001, significant difference from morphine alone; dP < 0.001, significant difference from CME 50 mg/kg alone; eP < 0.001, significant difference from CME 100 mg/kg alone, fP < 0.001, significant difference from CME 200 mg/kg alone.
![Figure 2. The antinociceptive effect of C. ovata extracts, morphine, dipyrone, and reversal effect of naloxone on the hot-plate test. Values are presented as the mean ± SEM (n = 6), (NLX; naloxone); aP < 0.001, significant difference from control; bP < 0.001, significant difference from dipyrone; cP < 0.001, significant difference from morphine alone; dP < 0.001, significant difference from CME 50 mg/kg alone; eP < 0.001, significant difference from CME 100 mg/kg alone, fP < 0.001, significant difference from CME 200 mg/kg alone.](/cms/asset/5569d98d-49c2-4301-820d-92ff099bfea5/iphb_a_463441_f0002_b.gif)
Figure 3. The antinociceptive effect of C. ovata extracts, morphine, dipyrone, and reversal effect of naloxone on acetic acid-induced writhing test. Values are presented as the mean ± SEM (n = 6), (NLX; naloxone); aP < 0.001, significant difference from control, cP < 0.001, significant difference from morphine alone.
![Figure 3. The antinociceptive effect of C. ovata extracts, morphine, dipyrone, and reversal effect of naloxone on acetic acid-induced writhing test. Values are presented as the mean ± SEM (n = 6), (NLX; naloxone); aP < 0.001, significant difference from control, cP < 0.001, significant difference from morphine alone.](/cms/asset/535d01f7-e2aa-45e8-82ae-036397e935be/iphb_a_463441_f0003_b.gif)