1,054
Views
19
CrossRef citations to date
0
Altmetric
Research Article

Screening of marine extracts for schistosomicidal activity in vitro. Isolation of the triterpene glycosides echinosides A and B with potential activity from the Sea Cucumbers Actinopyga echinites and Holothuria polii

, , , &
Pages 490-496 | Received 06 Mar 2011, Accepted 14 Aug 2011, Published online: 02 Dec 2011

Figures & data

Table 1.  Marine organisms screened for schistosomicidal activity in vitro.

Table 2.  LC50 and LC90 (μg/ml) of active marine organisms.

Table 3.  LC50 and LC90 (μg/ml) of echinosides A and B.

Figure 1.  Chemical structures of echinosides A and B. Echinoside A: R = 3-O-methyl-β-d-glucopyranosyl-(1→3)-β-d-glucopyranosyl-(1→4)-β-d-qinovopyranosyl-(1→2)-4-O-sodiosulphato-β-d-xylopyranosyl-. Echinoside B: R= β-d-quinovopyranosyl-(1→2)-4-O-sodiosulphato-β-d-xylopyranosyl-.

Figure 1.  Chemical structures of echinosides A and B. Echinoside A: R = 3-O-methyl-β-d-glucopyranosyl-(1→3)-β-d-glucopyranosyl-(1→4)-β-d-qinovopyranosyl-(1→2)-4-O-sodiosulphato-β-d-xylopyranosyl-. Echinoside B: R= β-d-quinovopyranosyl-(1→2)-4-O-sodiosulphato-β-d-xylopyranosyl-.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.