Figures & data
Table 1. Effect of methanol extract of A. aspera on wound area and percent wound contraction in experimental burn wounds in rats.
Table 2. Effect of methanol extract of A. aspera (MEAA) on antioxidant and biochemical parameters in burn wounds on eighth day post wounding in rats.
Figure 1. (A) Expression of standard marker proteins (Broad Range, BIO RAD, 10% SDS-PAGE) and (B) Matrix metalloproteinase expression by gelatin zymography (10% SDS-PAGE, 1 g/L gelatin) in methanol leaf extract of A. aspera (MEAA)-treated and untreated burn wound tissue of experimental rats after 7 days of treatment.
Figure 2. Photomicrograph showing histopathological changes of the granulation tissues in burn wound in rats, (A) Control group showing necrotic debris (H&E × 100), (B) MEAA-treated group showing collagen deposition (Vangiesons × 100), (C) MEAA-treated group showing collagen and fibroblast proliferation and formation of epidermis (H&E×100) and, (D) Himax-treated standard group showing congestion, development of epidermis and keratin layer (H&E × 100).
Figure 3. Photographs of the inflicted burn wounds in rats. (A) Control group, (B) MEAA-treated group, (C) Himax-treated standard group.
Table 3. Effect of methanol extract of A. aspera (MEAA) on hematological and biochemical in acute oral toxicity study.
Table 4. Effect of methanol extract of A. aspera (MEAA) on body weight (g), organ weights relative to body weight (g %), hematological and serum biochemical parameters in subacute dermal toxicity study.