Schistosomicidal evaluation of flavonoids from two species of Styrax against Schistosoma mansoni adult worms

Figures & data

Figure 1.  Chemical structures of the isolated compounds.

Table 1.  In vitro effects of the crude extracts, EtOAc fractions, and compounds from S. camporum and S. pohlii against S. mansoni adult worms.

Group	Incubation period (h)	Percentage of separated worms	Percentage of dead worms
1% DMSO	24 h	0	0
	120 h	0	0
Control^a	24 h	0	0
	120 h	0	0
PZQ^b	24 h	0	100
	120 h	0	100
EE-SC^c	24 h	100	0
	120 h	100	25
EF-SC^c	24 h	100	0
	120 h	100	0
EE-SP^c	24 h	0	0
	120 h	0	0
EF-SP^c	24 h	100	0
	120 h	100	100
1^d	24 h	0	0
	120 h	0	0
2^d	24 h	0	0
	120 h	100	0
3^d	24 h	0	0
	120 h	0	0
4^d	24 h	100	0
	120 h	100	25

^aRPMI 1640.

^bTested concentration 10 µM.

^cTested concentration 100 µg/mL.

^dTested concentration 100 µM.