Regulation of aortic extracellular matrix synthesis via noradrenergic system and angiotensin II in juvenile rats

Figures & data

Table 1.  Body weight, and mean water uptake during the experiments.

	Body weights (age of 6 weeks) (g)	Mean water intake (mL/kg/day)
CTRL	52 ± 3	80.9 ± 18
Gua	49 ± 5	83 ± 16
Los	54± 5	84.2 ± 22
Gua + Los	50 ± 6	79.6 ± 15

CTRL, control, Gua, sympathectomy group; Gua + Los, combined treatment group; Los, losartan-treated group.

Figure 1  . Quantitative real-time RT-PCR analysis of collagen type I and III (A) and elastin (B) in the aorta from control and treated rats. Values are presented as ratio of mRNA to 18S rRNA. Data are mean ± SEM, n = 10 in each group. *p < 0.05, **p < 0.01 (versus CRTL), τp < 0.05, ττp < 0.01 (versus Gua group), §p < 0.05, ^§§p < 0.01 (versus Los group). CTRL: control, Gua: sympathectomy group, Los: losartan-treated group, Gua + Los: combined treatment group.

Figure 2  . Immunoblot analysis and densitometric quantification of collagen I (A) and III (B) and elastin (C) in the aorta from control and treated rats. Values are presented here as ratio of collagen I, collagen III or elastin content to β-actin. Data are mean ± SEM; n = 10 in each group. *p < 0.05 (versus CRTL), τp < 0.05 (versus Gua group), ^§p < 0.05 (versus Los group). CTRL: control group, Gua: sympathectomy group, Los: losartan-treated group, Gua + Los: combined treatment group.