Figures & data
Figure 1. Effect of H. perforatum extract (Hp Ext) on naloxone (NLX)-induced opium withdrawal jumps in rats. Each column represents the mean ± SEM (n = 9). *p < 0.05, values significantly different as compared to saline (ANOVA followed by Dunnett’s post-hoc test). SAL = Saline.
Figure 2. Effect of H. perforatum extract (Hp Ext) on naloxone (NLX)-induced opium withdrawal wet dog shakes in rats. Each column represents the mean ± SEM (n = 9). *p < 0.05, values significantly different as compared to saline (ANOVA followed by Dunnett’s post-hoc test). SAL = Saline.
Figure 3. Effect of H. perforatum extract (Hp Ext) on naloxone (NLX)-induced opium withdrawal diarrhea in rats. Each column represents the mean ± SEM (n = 9). *p < 0.05, values significantly different as compared to saline (ANOVA followed by Dunnett’s post-hoc test). SAL = Saline.
Figure 4. Effect of H. perforatum extract (Hp Ext) on naloxone (NLX)-induced opium withdrawal hypothermia. Values shown are mean ± SEM (n = 9). *p < 0.05, **p < 0.01, values significantly different as compared to saline (ANOVA followed by Student’s t test). SAL = Saline.
Figure 5. Effect of H. perforatum extract (Hp Ext) on naloxone (NLX)-induced opium withdrawal salivation (a), squeal on touch (b), lying painting (c) and ptosis (d). Values shown are mean ± SEM (n = 9). p > 0.05, values not significantly different as compared to saline (ANOVA followed by Dunnett’s post-hoc test). SAL = Saline.
