Figures & data
Table 1. Effects of sophocarpine on hemodynamics and cardiac coefficient.
Figure 2. Effects of sophocarpine on the levels of plasma pro-inflammatory cytokines. Values are expressed as the mean ± SD, n = 9–11 animals. Significance was determined by ANOVA followed by Tukey’s test. ##p < 0.01 compared with the sham group; *p < 0.05 and **p < 0.01 compared with the model group.
![Figure 2. Effects of sophocarpine on the levels of plasma pro-inflammatory cytokines. Values are expressed as the mean ± SD, n = 9–11 animals. Significance was determined by ANOVA followed by Tukey’s test. ##p < 0.01 compared with the sham group; *p < 0.05 and **p < 0.01 compared with the model group.](/cms/asset/9691f355-32d4-43b2-8b47-4c3edca72840/iphb_a_877038_f0002_b.jpg)
Figure 3. Effects of sophocarpine on collagen content level. Values are expressed as the mean ± SD, n = 9–11 animals. Significance was determined by ANOVA followed by Tukey’s test. ##p < 0.01 compared with the sham group; *p < 0.05 and **p < 0.01 compared with the model group.
![Figure 3. Effects of sophocarpine on collagen content level. Values are expressed as the mean ± SD, n = 9–11 animals. Significance was determined by ANOVA followed by Tukey’s test. ##p < 0.01 compared with the sham group; *p < 0.05 and **p < 0.01 compared with the model group.](/cms/asset/780136cc-29e2-4676-bdf8-6ffccbcebbfc/iphb_a_877038_f0003_b.jpg)
Figure 4. Effect of sophocarpine on cardiac fibrosis (Masson’s trichrome staining, × 200): (A) sham-operated rats (n = 9), (B) model rats (n = 11), (C) rats treated with sophocarpine 10 mg/kg (n = 9), (D) rats treated with sophocarpine 20 mg/kg (n = 9), and (E) rats treated with sophocarpine 40 mg/kg (n = 10).
![Figure 4. Effect of sophocarpine on cardiac fibrosis (Masson’s trichrome staining, × 200): (A) sham-operated rats (n = 9), (B) model rats (n = 11), (C) rats treated with sophocarpine 10 mg/kg (n = 9), (D) rats treated with sophocarpine 20 mg/kg (n = 9), and (E) rats treated with sophocarpine 40 mg/kg (n = 10).](/cms/asset/878176eb-c41e-4125-8510-ab6c4b8d4b1c/iphb_a_877038_f0004_b.jpg)