Figures & data
Table 1. Endophytic fungal strains and their TLC screening results.
Figure 1. Morphological characteristics of strain TW5: colony on a PDA plate (a); microscopic examination of the structures of mature sporangium and sporangiophore (200×) (b); and the shape of the sporangiospore (400×) (c).
![Figure 1. Morphological characteristics of strain TW5: colony on a PDA plate (a); microscopic examination of the structures of mature sporangium and sporangiophore (200×) (b); and the shape of the sporangiospore (400×) (c).](/cms/asset/b4c95034-4c6f-4fd8-8145-96f987be43a3/iphb_a_885061_f0001_b.jpg)
Figure 2. Neighbor-joining trees based on the partial ribosomal gene sequences of strain TW5 and its closest relatives. The scale bar indicates a 2% estimated difference in the nucleotide sequence. GenBank accession numbers are shown in parentheses.
![Figure 2. Neighbor-joining trees based on the partial ribosomal gene sequences of strain TW5 and its closest relatives. The scale bar indicates a 2% estimated difference in the nucleotide sequence. GenBank accession numbers are shown in parentheses.](/cms/asset/aa30be8e-1060-470c-93c4-9c5fe2c157dd/iphb_a_885061_f0002_b.jpg)
Figure 3. Growth curve of M. fragilis (strain TW5). The error bars represent the standard deviations from the mean value of three flasks.
![Figure 3. Growth curve of M. fragilis (strain TW5). The error bars represent the standard deviations from the mean value of three flasks.](/cms/asset/2252a4bf-7494-46ac-9837-9446c9249c69/iphb_a_885061_f0003_b.jpg)
Figure 4. HPLC chromatograms of standard podophyllotoxin (a), fungal podophyllotoxin (b), standard kaempferol (c), and fungal kaempferol (d).
![Figure 4. HPLC chromatograms of standard podophyllotoxin (a), fungal podophyllotoxin (b), standard kaempferol (c), and fungal kaempferol (d).](/cms/asset/2a9e421d-40c2-4a0f-bef2-26c003493ffd/iphb_a_885061_f0004_b.jpg)
Figure 5. Chemical structures of podophyllotoxin (a) and kaempferol (b). Numbers represent the carbon positions.
![Figure 5. Chemical structures of podophyllotoxin (a) and kaempferol (b). Numbers represent the carbon positions.](/cms/asset/1b2b776d-9b32-47aa-bbdb-bbdbcd2d0941/iphb_a_885061_f0005_b.jpg)
Table 2. 1H- and 13C-NMR characterization of fungal podophyllotoxin.
Table 3. 1H- and 13C-NMR characterization of fungal kaempferol.