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Short Communication

Hepatoprotective effect of ethanol extract from Berchemia lineate against CCl4-induced acute hepatotoxicity in mice

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Pages 767-772 | Received 09 Nov 2013, Accepted 28 Jun 2014, Published online: 28 Nov 2014

Figures & data

Figure 1. Experimental design scheme.

Figure 1. Experimental design scheme.

Figure 2. Effects of BELE on the serum ALT (a), AST (b), ALP (c), TBIL (d), ALB (e), GLB (f), and TP (g). ##p < 0.01, ###p < 0.001 versus the vehicle-control group (control); *p < 0.05, **p < 0.01, and ***p < 0.001 versus vehicle with the CCl4 group (model).

Figure 2. Effects of BELE on the serum ALT (a), AST (b), ALP (c), TBIL (d), ALB (e), GLB (f), and TP (g). ##p < 0.01, ###p < 0.001 versus the vehicle-control group (control); *p < 0.05, **p < 0.01, and ***p < 0.001 versus vehicle with the CCl4 group (model).

Figure 3. Effects of BELE on the hepatic SOD (a) content and MDA (b) activity. ###p < 0.001 versus the vehicle-control group (control); *p < 0.05, **p < 0.01, and ***p < 0.001 versus vehicle with the CCl4 group (model).

Figure 3. Effects of BELE on the hepatic SOD (a) content and MDA (b) activity. ###p < 0.001 versus the vehicle-control group (control); *p < 0.05, **p < 0.01, and ***p < 0.001 versus vehicle with the CCl4 group (model).

Figure 4. Effects of BELE on hepatic morphological analysis (× 400 H&E): control group (a), CCl4-model group (b), Silymarin + CCl4 group (c), BELE 100 mg/kg + CCl4 group (d), BELE 200 mg/kg + CCl4 group (e), and BELE 400 mg/kg + CCl4 group (f) (*inflammatory infiltration; #dilated sinusoidal spaces).

Figure 4. Effects of BELE on hepatic morphological analysis (× 400 H&E): control group (a), CCl4-model group (b), Silymarin + CCl4 group (c), BELE 100 mg/kg + CCl4 group (d), BELE 200 mg/kg + CCl4 group (e), and BELE 400 mg/kg + CCl4 group (f) (*inflammatory infiltration; #dilated sinusoidal spaces).

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