The monoamine oxidase inhibitory activity of essential oils obtained from Eryngium species and their chemical composition

Figures & data

Table 1. Chemical composition of the essential oils obtained from Eryngium floribundum (EF), Eryngium eriophorum (EE), Eryngium nudicaule (EN), Eryngium horridum (EH), and Eryngium pandanifolium (EP).

Compound	RI^a	EF%	EE%	EN%	EH%	EP%
α-Pinene	927	–	t	–	–	–
β-Pinene	970	–	t	–	–	–
Limonene	1024	–	t	–	–	–
cis-Chrysanthenyl acetate	1255	6.0	–	–	–	–
Bornyl acetate	1278	–	–	–	–	t
n-Tridecane	1294	–	–	–	t	–
α-Terpinyl acetate	1341	–	–	–	t	–
2,3,6-Trimethyl benzaldehyde	1351	15.7	–	–	–	–
α-Copaene	1364	–	t	t	–	t
β-Bourbonene	1373	0.8	–	–	–	–
β-Elemene	1381	3.3	5.4	0.9	–	4.0
n-Tetradecane	1390	–	–	–	t	–
2-epi-β-Funebrene	1399	–	–	0.1	–	1.4
β-Funebrene	1400	2.9	–	–	–
(E)-Caryophyllene	1406	4.9	7.1	10.8	–	5.2
β-Copaene	1415	0.1	–	–	–	t
α-Cedrene	1416	–	–	–	t	–
cis-Thujopsene	1417	–	1.2	–	–	–
α-trans–Bergamotene	1424	–	–	t	–	–
Aromadendrene	1424	0.2	–	–	9.1	–
(Z)-β-Farnesene	1432	–	–	t	–	–
α-Humulene	1439	0.4	2.7	4.7	–	0.3
allo-Aromadendrene	1446	–	–	–	1.6	–
(E)-β-Farnesene	1447	t	–	1.6	–	–
Dauca-5,8–diene	1457	–	–	t	–	–
β-Acoradiene	1460	t	–	–	–	–
γ-Decalactone	1460	–	–	–	7.4	–
10-epi-β-Acoradiene	1462	–	–	5.6	–	–
γ-Muurolene	1465	t	–	1.8	–	–
Germacrene D	1469	0.6	35.1	5.4	–	28.9
β-Selinene	1473	–	1.8	–	–	3.3
Viridiflorene	1481	t	–	–	–	–
Bicyclogermacrene	1486	–	10.4	17.2	–	12.8
α-Muurolene	1487	–	–	–	–	t
trans-β-Guaiene	1489	–	–	5.0	–	–
Cuparene	1490	t	–	–	–	–
Pentadecane	1490	–	–	–	53.5	–
Germacrene A	1492	–	3.8	1.0	–	2.2
β-Bisabolene	1496	0.2	2.9	7.5	–	–
(Z)-γ-Bisabolene	1503	–	–	1.4	–	–
γ-Amorphene	1509	–	1.3	–	–	–
δ-Cadinene	1511	–	–	1.3	–	3.0
Dauca-4(11),8-diene	1514	–	t	–	–	–
Silphiperfol-5-en-3-one B	1535	–	0.8	–	–	–
epi-Longipinanol	1538	t	–	–	–	–
Germacrene B	1543	–	t	–	–	4.4
(E)-Nerolidol	1554	–	t	0.1	–	t
Longipinanol	1567	–	–	4.6	–	–
Spathulenol	1568	36.0	6.2	–	0.4	6.4
Caryophyllene oxide	1570	–	3.3	–	–	4.3
Globulol	1576	7.0	1.4	–	18.6	1.8
Salvial-4(14)-en-1-one	1581	–	1.5	–	–	2.0
Viridiflorol	1582	5.0	–	0.3	4.6	–
Cedrol	1590	–	–	1.2	–	–
Rosifoliol	1592	2.7	–	–	t	–
Guaiol	1595	–	–	t	–	–
Khusimone	1596	t	–	–	–	–
Humulene epoxide II	1597	–	–	t	–	–
Junenol	1605	–	–	–	–	t
cis-Cadin-4-en-7-ol	1621	–	–	–	–	t
allo-Aromadendrene epoxide	1625	–	t	–	–	t
3-iso-Thujopsanone	1637	–	1.2	–	–	–
Cubenol	1637	–	–	–	–	t
α-Muurolol	1638	–	–	t	–	t
α-Cadinol	1645	4.9	4.9	–	–	11.1
γ-Dodecalactone	1668	1.8	–	–	–	–
Khusinol	1670	–	–	–	–	t
α-Bisabolol	1675	0.1	2.9	–	–	1.0
Germacra-4(15),5,10(14)-trien-1-α-ol	1677	t	–	–	–	–
Eudesma-4(15),7-dien-1-β-ol	1678	–	t	0.9	–	–
(E)-Nerolidol acetate	1692	–	–	t	–	–
Mint sulfit	1723	–	–	1.4	–	–
Isobicyclogermacrenal	1724	t	0.2	1.8	–	–
Cyclocolorenone	1730	–	–	14.7	–	–
α-Sinesal	1743	–	–	1.4	–	–
Hexadecanal	1803	–	–	–	t	–
Total		92.5	94.1	90.7	95.2	92.1

^aRelative retention index experimentally determined against n-alkanes on Durabond-DB5 column; t = trace.

Figure 1. Inhibitory effect (%) of Eryngium floribundum (EF), Eryngium eriophorum (EE), Eryngium nudicaule (EN), Eryngium horridum (EH), and Eryngium pandanifolium (EP) on monoamine oxidase B activity. The samples were evaluated at 40 and 4 μg mL⁻¹. Error bars represent standard deviation (n = 3).