Figures & data
Figure 1. Triterpenoids from S. brasiliensis.
Table 1. NMR spectroscopic data of compound 1 (400 MHz, pyridine-d5).
Figure 2. Circular dichroism of cayaponosides A1 (2), B4 (3) and D (4).
Figure 3. Glycemia (A; mmol/L), glycosuria (B; mmol/24 h) and urinary urea (C; mmol/24 h) of STZ-diabetic rats treated for 21 days with S. brasiliensis extract. Values are expressed as means ± SEM, n = 5–8 per group. Differences between groups were analysed with one-way ANOVA followed by Student–Newman–Keuls test (p < 0.05). *Differences with N; #differences with DC; Φdifferences with DSb250; ɛdifferences with DSb500.
Figure 4. Body weight (A; g), food intake (B; g/24 h), water intake (C; mL/24 h) and urinary volume (D; mL/24 h) of STZ-diabetic rats treated for 21 days with S. brasiliensis extract. Values are expressed as means ± SEM, n = 5–8 per group. Differences between groups were analysed with one-way ANOVA followed by Student–Newman–Keuls test (p < 0.05). *Differences with N; #differences with DC; Φdifferences with DSb250; ɛdifferences with DSb500.
Table 2. Weight of liver, white adipose tissues (retroperitoneal, perirenal, epididymal), skeletal muscles (soleus, extensor digitorum longus, gastrocnemius) and liver glycogen content of STZ-diabetic rats treated for 21 days with S. brasiliensis extract.