1,830
Views
22
CrossRef citations to date
0
Altmetric
Research Article

Therapeutic role of quercetin on oxidative damage induced by acrylamide in rat brain

, , , &
Pages 1763-1767 | Received 17 May 2015, Accepted 01 Dec 2015, Published online: 05 Jan 2016

Figures & data

Figure 1. Effects of quercetin and acrylamide treatment on serotonin levels in the cerebral cortex of Wistar rats. Enzyme activity is expressed as ng/100 mg (n = 6). *p < 0.001 when compared with the control group (independent samples t-test between the control and the treated groups in brain). NSNon-significant as compared with the quercetin alone or quercetin and acrylamide (independent samples t-test between the control and the treated groups in brain).

Figure 1. Effects of quercetin and acrylamide treatment on serotonin levels in the cerebral cortex of Wistar rats. Enzyme activity is expressed as ng/100 mg (n = 6). *p < 0.001 when compared with the control group (independent samples t-test between the control and the treated groups in brain). NSNon-significant as compared with the quercetin alone or quercetin and acrylamide (independent samples t-test between the control and the treated groups in brain).

Figure 2. Effects of quercetin and acrylamide treatment on interferon-γ levels in the cerebral cortex of Wistar rats. Enzyme activity is expressed as pg/100 mg (n = 6). ***p < 0.0001 when compared with the control group (independent samples t-test between the control and the treated groups in brain). NSNon-significant as compared with quercetin alone or quercetin and acrylamide (independent samples t-test between the control and the treated groups in brain).

Figure 2. Effects of quercetin and acrylamide treatment on interferon-γ levels in the cerebral cortex of Wistar rats. Enzyme activity is expressed as pg/100 mg (n = 6). ***p < 0.0001 when compared with the control group (independent samples t-test between the control and the treated groups in brain). NSNon-significant as compared with quercetin alone or quercetin and acrylamide (independent samples t-test between the control and the treated groups in brain).

Figure 3. Effects of quercetin and acrylamide treatment on dopamine levels in the cerebral cortex of Wistar rats. Enzyme activity is expressed as ng/100 mg (n = 6). *p < 0.001 when compared to control group, ***p < 0.0001 when compared to control group (independent samples t-test between the control and the treated groups in brain).

Figure 3. Effects of quercetin and acrylamide treatment on dopamine levels in the cerebral cortex of Wistar rats. Enzyme activity is expressed as ng/100 mg (n = 6). *p < 0.001 when compared to control group, ***p < 0.0001 when compared to control group (independent samples t-test between the control and the treated groups in brain).

Figure 4. Effects of quercetin and acrylamide treatment on 8-hydroxyguanine levels in the cerebral cortex of Wistar rats. Enzyme activity is expressed as ng/100 mg (n = 6). *p < 0.001 when compared to control group, ***p < 0.0001 when compared to control group (independent samples t-test between the control and the treated groups in brain). There was found significant difference between ACR alone and quercetin+ACR group showing the partial protection in quercetin+ACR group.

Figure 4. Effects of quercetin and acrylamide treatment on 8-hydroxyguanine levels in the cerebral cortex of Wistar rats. Enzyme activity is expressed as ng/100 mg (n = 6). *p < 0.001 when compared to control group, ***p < 0.0001 when compared to control group (independent samples t-test between the control and the treated groups in brain). There was found significant difference between ACR alone and quercetin+ACR group showing the partial protection in quercetin+ACR group.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.