Figures & data
Figure 1. Disposition of randomized patients through the 2 years. Patients who discontinued MTX were excluded from further analyses.
Table 1. Baseline characteristics of randomized patients.
Figure 2. Effects of BUC on the flare rate after IFX discontinuation. *P = 0.045 versus MTX group by Fisher's exact test.
Figure 3. Comparison of treatment survival by Kaplan–Meier analysis. (A) Overall treatment survival was compared between BUC + MTX (circles connected by solid lines) and MTX groups (squares connected by dashed lines). P = 0.427 by Log-rank test. (B) Treatment survival focused on flare favored the BUC + MTX group (circles connected by solid lines) over the MTX group (squares connected by dashed lines). *P = 0.017 by Log-rank test.
Table 2. Comparisons between patients with and without flares.
Figure 4. Comparison of flare rates stratified by treatment groups and the achievement of remission by ACR/EULAR Boolean definition upon IFX discontinuation. *P = 0.014 versus Boolean remission (–) in the MTX group by Fisher's exact test.
