Figures & data
Table 1. Patient characteristics at baseline.
![Figure 1. MBDA scores at baseline and after 52 weeks of treatment with TNF inhibitors (N = 147). Box and whisker plot of MBDA scores at baseline and 52 weeks after initiation of TNF inhibitor treatment (ADA, ETN, and IFX). Thick horizontal line: median value; box: interquartile range (IQR); whiskers: most extreme points within 1.5 times the IQR from the limits of the box. ADA: adalimumab; ETN: etanercept; IFX: infliximab; MBDA: multi-biomarker disease activity; TNF: tumor necrosis factor.](/cms/asset/51e5d9ad-88db-434d-9828-ff7f78f259a5/imor_a_958893_f0001_b.gif)
![Figure 2. Scatterplot and regression lines for ΔDAS28-ESR (a) or ΔDAS28-CRP (b) versus ΔMBDA score from baseline to week 52, by TNF inhibitor. Each line was fitted by least square error separately for each group. ADA: adalimumab; DAS28-ESR: Disease Activity Score-28 with erythrocyte sedimentation rate; ETN: etanercept; IFX; infliximab; MBDA: Multi-biomarker disease activity; TNF: tumor necrosis factor.](/cms/asset/8b51e0ba-4296-4460-8901-018f5943f314/imor_a_958893_f0002_b.gif)
![Figure 3. Changes (Δ) in MBDA score by EULAR response at week 52. Box and whisker plot of ΔMBDA score from baseline to 52 weeks after initiation of TNF inhibitor treatment in patients with no, moderate, and good treatment response at 52 weeks as defined by EULAR criteria. Statistical significance of the difference between the responder groups was assessed by Wilcoxon's rank-sum test. Thick horizontal line: median; box: interquartile range (IQR); whiskers: most extreme points within 1.5 times the IQR from the limits of the box. BL: baseline; EULAR: European League Against Rheumatism; IQR: interquartile range; MBDA: multi-biomarker disease activity; TNF: tumor necrosis factor.](/cms/asset/fc82f3e0-8cc6-421b-9d9e-8d7a8aa11c24/imor_a_958893_f0003_b.gif)
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