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Research Article

Antifibrotic activity of triterpenoids from the aerial parts of Euscaphis japonica on hepatic stellate cells

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Pages 1276-1279 | Received 05 Nov 2008, Accepted 12 Feb 2009, Published online: 06 Oct 2009

Figures & data

Figure 1. Effect of total methanolic extract and the fractions of E. japonica on cell viability of HSC-T6 cells. HSC-T6 cells were incubated with test samples at the concentration of 10 or 100 μg/mL for 48 h. Cell viability was measured by the MTT assay. The percent of cell viability (%) was calculated as 100 × (absorbance of compound-treated/absorbance of control). Results are expressed as the mean ± SD of three independent experiments, each performed using triplicate wells. *p < 0.05, **p < 0.001 compared with control.

Figure 1.  Effect of total methanolic extract and the fractions of E. japonica on cell viability of HSC-T6 cells. HSC-T6 cells were incubated with test samples at the concentration of 10 or 100 μg/mL for 48 h. Cell viability was measured by the MTT assay. The percent of cell viability (%) was calculated as 100 × (absorbance of compound-treated/absorbance of control). Results are expressed as the mean ± SD of three independent experiments, each performed using triplicate wells. *p < 0.05, **p < 0.001 compared with control.

Figure 2. Triterpenoids isolated from the aerial parts of E. japonica.

Figure 2.  Triterpenoids isolated from the aerial parts of E. japonica.

Figure 3. Effect of triterpenoids isolated from E. japonica on cell viability of HSC-T6 cells. HSC-T6 cells were incubated with compounds at the concentration of 10 or 100 μM for 48 h. GA (β-glycyrrhetinic acid) was used as a positive control. Cell viability was measured by the MTT assay. The percent of cell viability (%) was calculated as 100 × (absorbance of compound-treated/absorbance of control). Results are expressed as the mean ± SD of three independent experiments, each performed using triplicate wells. *p < 0.05, **p < 0.001 compared with control.

Figure 3.  Effect of triterpenoids isolated from E. japonica on cell viability of HSC-T6 cells. HSC-T6 cells were incubated with compounds at the concentration of 10 or 100 μM for 48 h. GA (β-glycyrrhetinic acid) was used as a positive control. Cell viability was measured by the MTT assay. The percent of cell viability (%) was calculated as 100 × (absorbance of compound-treated/absorbance of control). Results are expressed as the mean ± SD of three independent experiments, each performed using triplicate wells. *p < 0.05, **p < 0.001 compared with control.

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