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Research Article

Oxidases and oxygenases in regulation of neutrophil redox pathways in Behçet’s disease patients

, , , &
Pages 12-17 | Received 14 Feb 2011, Accepted 13 Mar 2011, Published online: 24 Jun 2011

Figures & data

Figure 1.  (A) Erythrocyte sedimentation rate and (B) C-reactive protein in Behçet disease patients.

Figure 1.  (A) Erythrocyte sedimentation rate and (B) C-reactive protein in Behçet disease patients.

Figure 2.  (A) Neutrophil superoxide release in Behçet disease patients and controls, both at basal conditions and in response to 10 µM formyl-methionyl-leucyl-phenylalanine (fMLP) stimulation. Values are mean ± SEM (n = 19–22). *p < 0.05 compared to basal. (B) Plasma MPO activity and (C) neutrophil MPO activity in Behçet disease patients and controls. Values are mean ± SD (n = 10–11). *p < 0.001. The boundary of the box closest to zero indicates the 25th percentile, a line within the box marks the median, and the boundary of the box farthest from zero indicates the 75th percentile. Whiskers above and below the box indicate the 90th and 10th percentiles. (D) Neutrophil COX activity in Behçet disease patients and controls. Values are mean ± SD (n = 8–9). *p < 0.001.

Figure 2.  (A) Neutrophil superoxide release in Behçet disease patients and controls, both at basal conditions and in response to 10 µM formyl-methionyl-leucyl-phenylalanine (fMLP) stimulation. Values are mean ± SEM (n = 19–22). *p < 0.05 compared to basal. (B) Plasma MPO activity and (C) neutrophil MPO activity in Behçet disease patients and controls. Values are mean ± SD (n = 10–11). *p < 0.001. The boundary of the box closest to zero indicates the 25th percentile, a line within the box marks the median, and the boundary of the box farthest from zero indicates the 75th percentile. Whiskers above and below the box indicate the 90th and 10th percentiles. (D) Neutrophil COX activity in Behçet disease patients and controls. Values are mean ± SD (n = 8–9). *p < 0.001.

Table 1.  Plasma and neutrophil nitrite and nitrate levels in Behçet disease patients and controls.

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