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Research Article

A new class of 2-(4-cyanophenyl amino)-4-(6-bromo-4-quinolinyloxy)-6-piperazinyl (piperidinyl)-1,3,5-triazine analogues with antimicrobial/antimycobacterial activity

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Pages 370-379 | Received 27 Apr 2011, Accepted 18 May 2011, Published online: 08 Jul 2011

Figures & data

Figure 1.  Schematic diagram for the synthesis of 2-(4-cyanophenyl amino)-4-(6-bromo-4-quinolinyloxy)-6-piperazinyl (piperidinyl)-1,3,5-triazines.

Figure 1.  Schematic diagram for the synthesis of 2-(4-cyanophenyl amino)-4-(6-bromo-4-quinolinyloxy)-6-piperazinyl (piperidinyl)-1,3,5-triazines.

Figure 2.  [4(a-u), R] = Piperazine and piperidine bases coupled to compound 3.

Figure 2.  [4(a-u), R] = Piperazine and piperidine bases coupled to compound 3.

Table 1.  In vitro antimicrobial activity of newly synthesized compounds.

Table 2.  In vitro antifungal activity of newly synthesized compounds.

Table 3.  In vitro antimycobacterial activity of newly synthesized compounds.

Supplemental material

Supplementary Material

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