Scheme 1. Synthetic route for new Mannich base derivatives 3a–3e, 4a–4e, 5a–5e, 6a–6e.
Table 1. Substituents of compounds 1–6.
Table 2. Effects of tested compounds (3a, 3b, 3c, 3e, 4a, 4b, 4d, 5c, 5e, 6a, 6b, 6e) on the viability of chosen cell lines (%).
Table 3. The influence of synthesized compounds 1–6 on the growth of Gram-positive and Gram-negative bacteria of on the basis of MIC (µg/ml).
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