Advanced search
Publication Cover
Journal of Pain & Palliative Care Pharmacotherapy Volume 27, 2013 - Issue 1
Submit an article Journal homepage
442
Views
18
CrossRef citations to date
0
Altmetric
ARTICLE

The Role of Palliative External Beam Radiation Therapy in Boney Metastases Pain Management

Beilei CaiBeilei Cai, PhD, is a Postdoctoral Fellow, Pharmacotherapy Outcomes Research Center, College of Pharmacy, University of Utah, Salt Lake City, Utah, USA. Nickman, PhD, RPh, is Professor, Department of Pharmacotherapy, College of Pharmacy, University of Utah, Salt Lake City, Utah, USA. David K. Gaffney, MD, PhD, is Professor and Vice Chair of Radiation Oncology, School of Medicine and Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
,
Nancy A. NickmanBeilei Cai, PhD, is a Postdoctoral Fellow, Pharmacotherapy Outcomes Research Center, College of Pharmacy, University of Utah, Salt Lake City, Utah, USA. Nickman, PhD, RPh, is Professor, Department of Pharmacotherapy, College of Pharmacy, University of Utah, Salt Lake City, Utah, USA. David K. Gaffney, MD, PhD, is Professor and Vice Chair of Radiation Oncology, School of Medicine and Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.Correspondence[email protected]
&
David K. GaffneyBeilei Cai, PhD, is a Postdoctoral Fellow, Pharmacotherapy Outcomes Research Center, College of Pharmacy, University of Utah, Salt Lake City, Utah, USA. Nickman, PhD, RPh, is Professor, Department of Pharmacotherapy, College of Pharmacy, University of Utah, Salt Lake City, Utah, USA. David K. Gaffney, MD, PhD, is Professor and Vice Chair of Radiation Oncology, School of Medicine and Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
Pages 28-34 | Received 26 Sep 2012, Accepted 06 Dec 2012, Published online: 08 Feb 2013
 
Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days

ABSTRACT

Bone is the third most common organ affected by neoplastic metastases, and about 70% of patients with breast cancer or prostate cancer that develop metastases will have osseous involvement. As part of a multi-pronged approach to pain management in these patients, external beam radio therapy (EBRT) continues to be a mainstay of treatment for metastatic bone pain. This article reviews the role of radiation therapy in palliative management strategies for patients with bone metastases, including the clinical and cost-effectiveness of single fraction (SFRT) versus multiple fraction (MFRT) EBRT in pain relief. Studies indicate that SFRT is more cost-effective than MFRT, yet both are clinically effective in pain management. Therefore, EBRT use retains an important place among analgesia, bone modifying agents, chemotherapy, and hormone therapy in improving quality of life (QoL) and reducing morbidity from metastatic bone pain.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 65.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 553.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.