Canadian Cohort Obstructive Lung Disease (CanCOLD): Fulfilling the Need for Longitudinal Observational Studies in COPD

Figures & data

Figure 1.  CanCOLD study design and procedures.

Table 1.  Study evaluation forms and study flow chart

	Assessment	Initial visit	18 months	3 years
For all subjects of the cohort (4 subsets)	Informed consent form	X
	Core questionnaires, occupational & smoking	X	X	X
	Spirometry (pre & post BD)	X	X	X
	SF-36V2, HADS, CHAMPS, Past Exercise Habits, FFQ, General Health (VAS), Sleep questionnaires; CDLM & GCSQ, SF-HLQ	X	X	X
	PFT & CPET, PA & MDCT Scan*	X		X
	Blood Tests- Hematology, biochemistry, lipid profile; biomarkers, DNA for genetic, RNA for transcriptomic profiling	X	X	X
Only COPD and at-risk	SGRQ, CAT	X	X	X
	McGill COPD-specific module	X	X	X

CAT: COPD Assessment Test; CDLM : Capacity of Daily Living questionnaire; CHAMPS:; CPET: cardiopulmonary exercise test; FFQ: Food Frequency Questionnaire; GCSQ: Global Chest Symptoms Questionnaire; HADS: Hospital Anxiety and Depression Scale; MDCT Scan: multi detector CT Scan; PA: physical activity; PFT: pulmonary function test; SF-36V2: Short Form-36 version 2; SF-HLQ: Short form of the Health and Labour Questionnaire; SGRQ: St. George's Respiratory Questionnaire;

* CT Scan of the chest will only be done once for subjects of the subset “normal respiratory health.

Figure 2.  Quality control flow chart.