The COPD Assessment Test (CAT): Short- and Medium-term Response to Pulmonary Rehabilitation

Figures & data

Table 1.  Baseline characteristics

Age (years)	73 (8)
FEV1%	47 (33, 67)
Gender (M:F)	60:58
Body Mass Index (kg.m-2)	28.5 (23.9, 32.0)
ISW (metres)	130 (50, 250)
CRQ Dyspnoea	13 (8, 16)
CRQ Fatigue	13 (10, 17)
CRQ Emotion	31 (25, 38)
CRQ Mastery	20 (14, 23)
CRQ Total	75 (58, 91)
CAT score	22.1 (7.5)

Data expressed as mean (standard deviation) or median (25th, 75th centile).

Table 2.  Response to PR (T2-T1)

	Pre-Pr (T1)	Post-PR (T2)	p-Value
CAT	22.1 (7.5)	19.2 (7.6)	<0.001
CRQ Dyspnoea	13 (8, 16)	16 (11, 22)	<0.001
CRQ Fatigue	13 (10, 17)	16.5 (5.7)	<0.001
CRQ Emotion	31 (25, 38)	34.7 (8.7)	<0.001
CRQ Mastery	20 (14, 23)	22 (16, 25)	<0.001
CRQ Total	75 (58, 91)	88.7 (24.1)	<0.001
ISW, metres	130 (50, 250)	215 (100, 320)	<0.001

Data presented as mean (standard deviation) or median (interquartile range).

Table 3.  Medium-term response to PR (T3-T2)

	Post-PR (T2)	6 months post-PR (T3)	p-Value
CAT	19.2 (7.6)	20.7 (7.6)	0.008
CRQ Dyspnoea	16 (11, 22)	15.5 (6.9)	0.02
CRQ Fatigue	16.5 (5.7)	14.7 (5.0)	<0.001
CRQ Emotion	34.7 (8.7)	32.9 (8.6)	0.001
CRQ Mastery	22 (16, 25)	20 (15, 25)	0.44
CRQ Total	88.7 (24.1)	86 (63, 98)	<0.001
ISW, metres	215 (100, 320)	170 (68, 300)	<0.001

Data presented as mean (standard deviation) or median (interquartile range).

Table 4.  Relationship between delta CAT, delta CRQ and delta ISW between T2-T1 and T3-T2

T2-T1 ΔCAT	r	p-value
ΔCRQ Total	-0.44	<0.001
ΔISW	-0.24	0.01
T3-T2 ΔCAT	r	p-value
ΔCRQ Total	-0.44	<0.001
ΔISW	-0.10	0.31

N = 118 except for ΔISW (114 observations) between T3-T2.

CRQ, self-report Chronic Respiratory Questionnaire; ISW, incremental shuttle walk.

Figure 1.  Mean (95% Confidence Intervals) COPD Assessment test (CAT) scores and median (interquartile range) Chronic Respiratory Disease Questionnaire (CRQ) total and domain scores plotted pre-, immediately post- and 6 months after pulmonary rehabilitation.

Figure 2.  Mean (95% Confidence Intervals) COPD Assessment test (CAT) scores and median (interquartile range) incremental shuttle walk plotted pre-, immediately post- and 6 months after pulmonary rehabilitation.

Figure 3.  Delta CAT versus delta CRQ between T1 and T2 and between T2 and T3. Filled circles represent T1-T2 and open circles represent T2-T3. Solid line represents T1-T2 regression line and dashed line represents T2-T3 regression line. ANCOVA: intercept p = 0.79, slope p = 0.95.