Use of an Australian Quality of Life Tool in Patients with COPD

Figures & data

Table 1.  Patient characteristics

Participant Characteristic	Mean	SD
Age	71	10
Male (N)	70
FEV1/FVC>0.70 (N)	33
FEV1/FVC<0.70 (N)	85
Stage I (N)	7
Stage II (N)	29
Stage III (N)	41
Stage IV (N)	8
PaO2	74.5	11.9
PCO2	38.2	5.6
FEV1	61.3	25
MMRC	2.3	1.2
6MWD	390	121
BMI	27.1	5.9
BODE	3.2	2.3

FEV1/FVC = Forced expiratory volume in one second/forced vital capacity; 
PaO2 = Partial pressure of oxygen in arterial blood sample; PCO2 = Partial pressure of carbon dioxide in arterial blood sample; FEV1 = Forced expiratory volume in one second post bronchodilator (% of predicted); MMRC = Modified Medical Research Council dyspnoea scale; 6MWD = Six Minute Walk Distance (metres); BMI = Body Mass 
Index (kg/m2).

Table 2.  Correlations between AQOL and other quality-of-life measures

	AQOL	SF36 PCS	SF36 MCS	Mean	SD
AQOL				.54	.29
SF36 physical function	.52			37	25
SF36 role –physical	.51			39	41
SF36 body pain	.44			65	29
SF36 vitality	.45			44	22
SF36 social functioning	.53			73	26
SF36 role –emotional	.47			69	41
SF36 mental health	.47			72	20
SF36 general health	.36			40	22
SF36; PCS	.68			45	21
SF36 MCS	.68			59	20
SGRQ symptoms	–.26	–.43	–.38	51	23
SGRQ activities	–.48	–.71	–.49	69	21
SGRQ impacts	–.62	–.69	–.68	38	41
SGRQ total	–.60	–.77	–.67	50	16

SD = Standard deviation SF36 PCS = SF36 physical component score, SF36 MCS = SF36 mental component score; AQOL = Assessment of Quality of Life; SGRQ = St George Respiratory Questionnaire.

Correlations of the 8 SF36 subscales are Spearman's rho. All other correlations are Pearson's R. All correlations significant to p < .05.

Table 3.  BODE and BODE Component Scores as Predictors of HRQOL

	Beta	∆R2	Beta	∆R2	Beta	∆R2	Beta	∆R2
	AQOL		SF36 PCS		SF36 MCS		SGRQ
BODE	–0.31**	0.10	–0.38***	0.14	–0.25*	0.05	0.51***	0.27
mMRC	–0.36***	0.11	–0.47***	0.19	–0.32**	0.08	0.57***	0.27
6MWD	0.39***	0.12	0.55***	0.23	0.46***	0.11	–0.64***	0.32
BMI	–0.11	0.02	–0.21*	0.03	–0.14	0.02	0.14	0.02
FEV1	0.08	0.01	0.03	0.00	–0.05	0.00	–0.20	0.05

*p = <.05, **p = <.01, ***p = <.001.
Where Beta is reported, the covariates age and sex were present in each model.
∆R2 = R2 for the model containing only the HRQOL measure of interest, age and sex were excluded.
AQOL = Assessment of Quality of Life; SF36 = Medical Outcomes 36-item Short Form Health Survey, PCS = Physical Component.
Score, MCS = Mental Component Score; SGRQ = St George Respiratory.

Figure 1.  Flow diagram for data collection