Pulmonary Rehabilitation Improves Sleep Quality in Chronic Lung Disease

Figures & data

Table 1  Clinical, demographic and anthropometric characteristics of the patients*

	All	Obstructive	Restrictive	Mixed
	N = 64	N = 46 (72%)	N = 13 (20%)	N = 5 (8%)
Age (years)	68.0 (10.2)	69.2 (10.5)	65.0 (9.4)	65.20 (9.3)
BMI (kg/m2)	28.1 (7.4)	26.5 (6.4)	29.4 (5.6)	39.9 (9.9)
Pulmonary Function
FEV1 (L)	1.3 (0.5)	1.1 (0.4)	1.8 (0.6)	1.6 (0.5)
FVC (L)	2.5 (0.8)	2.6 (0.8)	2.3 (0.8)	2.6 (1.1)
FEV1/FVC%	53.1 (18.9)	44.2 (12.3)	82.2 (6.8)	62.7 (11.5)
FEV1% pred	48.9 (17.4)	44.7 (16.3)	66.1 (12.4)	46.8 (13.7)
FVC% pred	72.5 (18.1)	76.3 (17.7)	63.4 (12.8)	59.3 (21.4)
			N (%)
Gender
Male	31 (48)	21 (46)	6 (46)	4 (80)
Female	33 (52)	25 (54)	7 (54)	1 (20)
Supplemental O2	28 (44)	19 (41)	6 (46)	3 (60)
Co-morbidities
Cardiac Disease	19 (30)	16 (35)	3 (25)	5 (100)
Hypertension	28 (44)	22 (48)	3 (23)	3 (60)
OSA	12 (19)	4 (9)	4 (31)	4 (80)
			M (SD)
PSQI Global Index	6.9 (3.9)	6.6 (3.9)	8.2 (3.7)	6.6 (4.7)
Subjective Sleep Quality	0.9 (0.7)	0.8 (0.7)	1.3 (0.8)	0.6 (0.5)
Sleep Latency	1.0 (1.1)	1.0 (1.0)	1.2 (1.1)	1.0 (1.4)
Sleep Duration	1.0 (1.0)	0.9 (1.0)	1.3 (1.1)	1.4 (0.9)
Sleep Efficiency	0.9 (1.1)	0.8 (1.1)	1.0 (0.9)	1.8 (1.6)
Sleep Disturbances	1.4 (0.6)	1.4 (0.6)	1.5 (0.7)	1.0 (0.7)
Use of Sleep Medication	0.8 (1.3)	0.9 (1.3)	0.9 (1.4)	0.0 (0.0)
Daytime Dysfunction	0.9 (0.6)	0.9 (0.7)	0.9 (0.5)	0.8 (0.4)
SOBQ	54.7 (19.7)	56.8 (20.1)	50.2 (15.2)	46.4 (25.6)
6-MW (meters)	350.8 (113.8)	339.2 (111.9)	399.3 (117.6)	328.5 (108.0)
SEW	3.5 (2.7)	3.5 (2.8)	3.3 (2.4)	4.7 (2.1)
SF-36 PCS	31.0 (7.9)	31.0 (8.2)	29.8 (5.5)	34.5 (1.1)
SF-36 MCS	52.9 (9.2)	52.6 (9.6)	54.8 (9.0)	49.9 (3.2)

*Results reported as mean (SD).

Table 2.  Results of the stepwise multiple regression analysis with the mental and the physical components of health-related quality of life as dependent variables

SF-36 MCS
	B	SE	β	Sig.	Partial R
PSQI	−1.20	0.26	−0.51	<0.001	−0.54
SOBQ	−0.21	0.06	−0.44	0.001	−0.34
SF36 PCS	−0.49	0.134	−0.42	0.002	−0.36
6-MW	−0.02	0.01	−0.26	0.038	−0.22
SF-36 PCS
	B	SE	β	Sig.	Partial R
PSQI	−0.68	0.24	−0.34	0.007	−0.36
SOBQ	−0.20	0.04	−0.50	<0.001	−0.53
SF36 MCS	−0.37	0.10	−0.43	0.001	−0.44

Table 3.  Baseline values and changes from baseline after pulmonary rehabilitation in obstructive and restrictive lung disease patients

	Obstructive		Restrictive
	Pre	Post	Pre	Post
PSQI Global Index	6.6 (3.9)	5.5 (3.6)*	8.2 (3.7)	8.3 (4.5)
Subjective Sleep Quality	0.7 (0.7)	0.6 (0.7)	1.3 (0.8)	1.2 (1.0)
Sleep Latency	0.9 (1.0)	0.8 (0.9)	1.2 (1.0)	0.9 (1.0)*
Sleep Duration	0.9 (1.0)	0.9 (1.1)	1.3 (1.1)	1.5 (1.0)
Sleep Efficiency	0.8 (1.1)	0.7 (1.0)	0.9 (0.9)	1.4 (1.1)
Sleep Disturbances	1.4 (0.6)	1.1 (0.5)**	1.5 (0.7)	1.5 (0.8)
Use of Sleep Medication	0.8 (1.2)	0.6 (1.1)	1.1 (1.5)	0.9 (1.4)
Daytime Dysfunction	0.9 (0.7)	0.7 (0.6)	0.9 (0.5)	0.8 (0.8)
SOBQ	56.0 (20.1)	43.1 (20.9)**	53.1 (19.9)	42.7 (19.7)
6-MW (meters)	343.7(109.0)	388.6(121.7)**	402.9(113.7)	456.1(97.4)**
SEW	3.6 (2.8)	4.4 (2.9)*	3.3 (2.4)	5.0 (2.5)*
SF-36 MCS	53.9 (8.6)	57.9 (7.3)**	54.8 (8.9)	56.7 (5.7)
SF-36 PCS	31.2 (8.3)	36.0 (8.9)**	29.8 (5.5)	33.0 (1.1)


* p < 0.05.

** p < 0.01.

#Results reported as mean (SD).