Effects of Whole Body Vibration in Patients With COPD

Figures & data

Figure 1. Consort diagram.

Table 1. Patient characteristics

Median (25P-75P)	WBVT (N = 31)	RT (N = 31)	P value
Age (year)	58 (55 – 73)	63 (57 – 68)	0.46
Gender (M/F)	21/10	23/8	0.56
FEV1 (L/min)	1.1 (0.5 – 1.5)	1.1 (0.5 – 1.5)	0.89
FEV1 (%)	38 (28 – 45)	39 (29 – 45)	0.58
FEV1 /FVC (%)	40 (34– 45)	37 (30 – 61)	0.67
BMI (kg/m2)	23 (20 – 25)	26 (23 – 29)	0.01
6MWD (m)	420 (355 – 480)	423 (301 – 503)	0.75
Wmax (Watt)	56 (45 – 78)	62 (36 – 82)	0.90
VO2 peak (ml/min)	1040 (790 – 1350)	1020 (950 – 1230)	0.60
QF (Nm)	99 (70 – 103)	103 (89 – 119)	0.33
ET 75% (min)	8 (5 – 10)	10 (6 – 18)	0.32
CRDQ (points)	74 (66 – 96)	77 (63 – 91)	0.92

WBVT: Whole Body Vibration Training; RT: Conventional Resistance Training; FEV1: Forced Expiratory Volume in 1 sec; FVC: Forced Vital Capacity; BMI: Body Mass Index; 6MWD: 6-Minute Walking Distance; Wmax: Maximal Workload; VO2 peak: Peak Oxygen Consumption; QF: Quadriceps Force; ET 75%: Endurance test on bicycle at 75% of maximal workload. CRDQ: Chronic Respiratory Disease Questionnaire.

Table 2. Effects of 12-week WBVT versus RT training in COPD patients

	WBVT N = 26			RT N = 25
Median (25P-75P)	Intake	12 weeks	∆ change	Intake	12 weeks	∆ change
BMI (kg/m2)	22 (20–25)	23* (20–26)	1 (1–2)	26 (24–28)	25 (22–28)	1 (0–1)
6MWD (m)	420 (330–480)	453* (389–519)	35 (14–76)	430 (327–511)	495* (425–555)	60 (13–96)
6MWD (%pred.)	64 (53–71)	70* (55-78)	6 (3–12)	67 (4–874)	75* (70–80)	10 (3–16)
Wmax (Watt)	55 (43–75)	57* (45–99)	7 (2–23)	67 (33–52)	72* (58–100)	12 (8–18)
Wmax (%pred.)	39 (29–55)	44* (33–63)	5 (1–14)	44 (35–61)	50* (39–75)	7 (6–14)
VO2 peak (mL/min)	1040 (790–1130)	1030 (890–1550)	30 (-60–200)	1060 (950–1130)	1170* (1040–1370)	130 (30–250)
VO2 peak (%pred.)	58 (46–68)	59 (47–74)	2 (-4–10)	60 (50–73)	61* (56–82)	6 (2–15)
QF (Nm)	92 (70–114)	96 (72–140)	9 (-16–29)	105 (90–122)	116* (100–162)	12 (-3–44)
QF (%pred.)	71 (63–86)	75 (58–92)	8 (-10–20)	70 (61–80)	85* (70–105)	10 (10–47)
ET 75% (min)	8 (5–10)	25* (16–32)	15 (7–20)	10 (6–18)	20* (13–26)	10 (1–17)
CRDQ (points)	72 (66–96)	92* (75–99)	13 (4–25)	75 (63–91)	94* (72–107)	11 (3–16)

WBVT: Whole Body Vibration Training; RT: Conventional Resistance training; BMI: Body Mass Index; 6MWD: 6-Minute Walking Distance; Wmax: Maximal Workload; VO₂ peak: Peak Oxygen Consumption; QF: Quadriceps Force; ET 75%: Endurance Test on bicycle at 75% of maximal workload; CRDQ: Chronic Respiratory Disease Questionnaire. P < 0.05: intake versus 12 weeks*.

Figure 2. Change in 6MWD after 12 weeks WBVT and RT.

Table 3. Responders to 12-weeks WBVT and RT training defined by MCID

	WBVT N = 26	RT N = 25
6MWD ≥54 m	31%	60%
Wmax ≥10 Watt	46%	73%
CRDQ ≥10 points	65%	52%

MCID: Minimally Clinical Important Differences; WBVT: Whole Body Vibration Training; RT: conventional Resistance Training; 6MWD: 6-Minute Walking Distance; Wmax: Maximal Workload; CRDQ: Chronic Respiratory Disease Questionnaire.