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Letter

Very late recovery of dapsone-induced methemoglobinemia

, , , &
Pages 80-81 | Received 16 Aug 2013, Accepted 05 Nov 2013, Published online: 06 Dec 2013

Figures & data

Fig. 1. Methemoglobin and dapsone serum levels after cessation of dapsone therapy. Day 0 = day of clinical presentation and cessation of dapsone therapy; •: Methemoglobin (%); □: Dapsone concentration (mg/L); : Methylene blue 1 mg/kg intravenously [Day 10 (twice), 11, 63, 185]; ....: Charcoal 50 g in 500 ml sodium sulfate (Carbomix®) twice daily orally (day 39–46); ---: Ascorbic acid 500 mg tablet thrice daily (Day 49 – end); –––: Cimetidine 400 mg tablet thrice daily (Day 106 – end).

Fig. 1. Methemoglobin and dapsone serum levels after cessation of dapsone therapy. Day 0 = day of clinical presentation and cessation of dapsone therapy; •: Methemoglobin (%); □: Dapsone concentration (mg/L); ↑: Methylene blue 1 mg/kg intravenously [Day 10 (twice), 11, 63, 185]; ....: Charcoal 50 g in 500 ml sodium sulfate (Carbomix®) twice daily orally (day 39–46); ---: Ascorbic acid 500 mg tablet thrice daily (Day 49 – end); –––: Cimetidine 400 mg tablet thrice daily (Day 106 – end).

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