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Original

The effect of glucocorticoids on tendon cell viability in human tendon explants

, , &
Pages 363-367 | Accepted 23 Feb 2009, Published online: 26 Oct 2009

Figures & data

Figure 1. Incubation of human tendon explants with 10 μM and 100 μM dexamethasone for 96 h reduced the fluorescence intensity of Alamar blue to mean 65% (SE 10) and 55% (SE 14) of the original values (n = 15 and n = 16, respectively). Mixed-effects ANOVA and post hoc tests showed significant suppression compared to the controls, the fluorescence intensity of which increased to mean 106% (SE 16) (n = 14).

Figure 1. Incubation of human tendon explants with 10 μM and 100 μM dexamethasone for 96 h reduced the fluorescence intensity of Alamar blue to mean 65% (SE 10) and 55% (SE 14) of the original values (n = 15 and n = 16, respectively). Mixed-effects ANOVA and post hoc tests showed significant suppression compared to the controls, the fluorescence intensity of which increased to mean 106% (SE 16) (n = 14).

Figure 2. Incubation of human tendon explants with 10 μM and 100 μM triamcinolone for 96 h reduced the fluorescence intensity of Alamar blue to mean 67% (SE 15) and 64% (SE 9) of the original values (n = 19 and n= 21, respectively). Mixed-effects ANOVA and post hoc tests showed significant suppression compared to the controls, the fluorescence intensity of which increased to mean 109% (SE 15) (n = 17).

Figure 2. Incubation of human tendon explants with 10 μM and 100 μM triamcinolone for 96 h reduced the fluorescence intensity of Alamar blue to mean 67% (SE 15) and 64% (SE 9) of the original values (n = 19 and n= 21, respectively). Mixed-effects ANOVA and post hoc tests showed significant suppression compared to the controls, the fluorescence intensity of which increased to mean 109% (SE 15) (n = 17).

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