A randomized, controlled trial comparing local infiltration analgesia with epidural infusion for total knee arthroplasty

Figures & data

Flow-chart of the study.

Table 1. Baseline data

	Group A	Group E
	(n = 21)	(n = 19)
Female / Male (n)	9 / 12	5 / 14
Age, years	67 (63–72)	69 (63–74)
Weight, kg	80 (65–89)	85 (71–88)
BMI	28 (25–32)	28 (26–31)
Smoking, yes/no	6 /15	4 /15
ASA physical status
I healthy	5	4
II mild systemic disease	16	13
III severe systemic disease	0	2
Duration of surgery, min	119 (94–139)	109 (85–120)

Values are given as frequencies or median with interquartile range in parentheses, where relevant.

Table 2. Morphine consumption, mg

	Group A (n = 21)	Group E (n = 19)	p-value
0–24 h	7.5 (2.5–15)	18 (13–32)	0.05
24–48 h	5 (0–8.8)	15 (5–23)	0.03
0–48 h	11 (3.8–23)	33 (20–40)	0.01

Values are given as median with interquartile range in parentheses. Mann-Whitney U test.

Table 3. Pain intensity score (VAS, 0–100 mm) at rest and during walking

	Group A (n = 21)	Group E (n = 19)	p-value
Rest
2–24	7 (3–25)	30 (10–44)	0.009
24–48	5 (2–21)	33 (9–38)	0.02
48–72	7.5 (2.5–21)	23 (14–42)	0.02
Walking
2–24	13 (4–41)	37 (12–53)	0.05
24–48	14 (7–35)	41 (27–51)	0.02
48–72	17 (4.5–36)	41 (24–53)	0.02

Values are given as median with interquartile range in parentheses. Mann-Whitney U test.