Patient-reported outcome after rheumatoid arthritis-related surgery in the lower extremities

Figures & data

Flow chart of patients.

Table 1. Orthopedic interventions

Intervention	n (%)
Forefoot arthrodesis	77 (29)
Stainsby	31 (11)
Hindfoot arthrodesis	37 (13)
Ankle arthroplasty	13 (5)
Ankle arthrodesis	17 (6)
THR	26 (9)
TKR	34 (12)
Forefoot osteotomy	18 (7)
Phalang resection	9 (3)
Hindfoot osteotomy	2 (1)
Knee arthroscopy	2 (1)
Others	9 (3)

Table 2. Patient characteristics

	Responders	Foot	Ankle	Knee	Hip	Non-responders
n	165	102	21	27	15	93
Women, n (%)	141 (86)	94 (92)	16 (76)	20 (74)	11 (73)	71 (76)
Age in years ^a	64 (11)	65 (11)	62 (13)	68 (9)	61 (14)	62 (13)
Preoperative HAQ score ^a	1.1 (0.58)	1.0 (0.56)	1.4 (0.56)	1.2 (0.58)	1.3 (0.60)	1.1 (0.60)
Preoperative SF-36 scores ^a, b
PF	39 (23)	44 (23)	28 (17)	35 (22)	28 (22)	41 (23)
RP	29 (39)	34 (41)	19 (32)	27 (37)	15 (31)	29 (36)
BP	37 (21)	40 (21)	34 (22)	36 (17)	25 (26)	36 (21)
GH	52 (21)	51 (21)	51 (19)	51 (20)	59 (22)	52 (22)
VT	47 (25)	51 (25)	38 (19)	48 (21)	33 (25)	45 (24)
SF	69 (26)	73 (26)	56 (25)	69 (23)	60 (31)	68 (25)
RE	58 (45)	64 (44)	51 (44)	42 (49)	60 (44)	62 (42)
MH	73 (19)	76 (19)	63 (22)	71 (18)	79 (21)	74 (19)

^a Values are mean (SD)

^b See Methods for a full explanation of the 8 dimensions of the SF-36.

Table 3. HAQ and SF-36 scores before and after surgery (n = 165)

	Baseline	6 months	12 months	Mean change (SD; CI)	p-value (Friedman's test)	p-value
HAQ score, mean (SD)	1.1 (0.58)	0.99 (0.62)	1.0 (0.62)	–0.11 (0.44; –0.18 to 0.041)	< 0.001	0.006
SF-36 scores, mean (SD)
PF	39 (23)	49 (24)	50 (25)	11 (23; 7.3–14)	< 0.001	< 0.001
RP	29 (39)	44 (41)	41 (42)	12 (41; 5.8–19 )	0.001	< 0.001
BP	37 (21)	52 (24)	50 (24)	13 (24; 9.5–17)	< 0.001	< 0.001
GH	52 (21)	52 (23)	50 (21)	–2.2 (19; –5.0 to 0.70)	0.6	0.2
VT	47 (25)	52 (24)	51 (23)	3.5 (21; 0.24–6.8)	0.1	0.08
SF	69 (26)	77 (25)	75 (26)	6.4 (24; 2.7–10)	< 0.001	0.001
RE	58 (45)	67 (42)	67 (42)	9.4 (48; 1.7–17)	0.2	0.01
MH	73 (19)	77 (20)	74 (20)	0.35 (19; –2.7 to 3.4)	0.2	0.6

Table 4. HAQ and SF-36 scores before and after surgery: foot (n = 102)

	Baseline	6 months	12 months	Mean change (SD; CI)	p-value
HAQ score, mean (SD)	1.0 (0.56)	0.97 (0.63)	0.96 (0.59)	–0.036 (0.41; -0.12-0.048)	0.8
SF-36 scores, mean (SD)
PF	44 (23)	50 (24)	51 (24)	7.4 (22; 3.1–12)	< 0.001
RP	34 (41)	45 (40)	42 (40)	8.4 (40; 0.32–17)	0.03
BP	40 (21)	49 (23)	48 (22)	8.0 (20; 3.9–12)	< 0.001
GH	51 (21)	50 (22)	49 (23)	–2.0 (20; –6.0 to 2.0)	0.4
VT	51 (25)	53 (24)	50 (24)	–1.0 (20; –4.9 to 2.9)	0.5
SF	73 (26)	76 (24)	75 (26)	1.7 (24; –3.0 to 6.5)	0.4
RE	64 (44)	66 (42)	67 (42)	3.0 (48; –6.7 to 13)	0.5
MH	76 (19)	77 (18)	72 (20)	–3.4 (20; –7.4 to 0.59)	0.1

Table 5. HAQ and SF-36 scores before and after surgery: ankle (n = 21)

	Baseline	6 months	12 months	Mean change (SD; CI)	p-value
HAQ score, mean (SD)	1.4 (0.56)	1.2 (0.53)	1.4 (0.53)	0.00 (0.41; –0.19 to 0.19)	0.8
SF-36 scores, mean (SD)
PF	27 (17)	36 (19)	33 (22)	5.1 (21; –4.3 to 15)	0.2
RP	19 (32)	26 (39)	27 (41)	8.3 (41; –10 to 27)	0.4
BP	34 (22)	55 (25)	46 (23)	13 (24; 2.0–23)	0.03
GH	51 (19)	52 (20)	46 (20)	–4.0 (14; –11 to 2.8)	0.2
VT	38 (19)	43 (27)	46 (19)	8.1 (20; –1.3 to 17)	0.2
SF	56 (25)	72 (30)	69 (32)	13 (21; 3.7–23)	0.02
RE	51 (44)	59 (45)	55 (46)	5.0 (56; –21 to 31)	0.7
MH	63 (22)	70 (23)	71 (18)	7.8 (20; –1.8 to 17)	0.1

Table 6. HAQ and SF-36 scores before and after surgery: knee (n = 27)

	Baseline	6 months	12 months	Mean change (SD; CI)	p-value
HAQ score, mean (SD)	1.2 (0.58)	1.0 (0.62)	1.0 (0.66)	–0.29 (0.29; –0.41 to –0.17)	< 0.001
SF-36 scores, mean (SD)
PF	35 (22)	52 (21)	55 (22)	20 (19; 12–27)	< 0.001
RP	27 (37)	50 (45)	51 (46)	26 (47; 6.9–44)	0.01
BP	36 (17)	53 (22)	58 (23)	21 (24; 12–31)	< 0.001
GH	51 (20)	49 (22)	50 (18)	–1.4 (16; –8.0 to 5.1)	0.8
VT	48 (21)	53 (22)	56 (21)	8.5 (18; 1.4–16)	0.02
SF	69 (23)	83 (21)	82 (20)	13 (20; 5.7–21)	0.003
RE	42 (49)	67 (44)	69 (41)	27 (46; 8.3–46)	0.007
MH	71 (18)	73(20)	76 (20)	5.1 (14; –0.32 to 11)	0.06

Table 7. HAQ and SF-36 scores before and after surgery: hip (n = 15)

	Baseline	6 months	12 months	Mean change (SD; CI)	p-value
HAQ score, mean (SD)	1.3 (0.60)	0.71 (0.66)	0.87 (0.72)	–0.44 (0.61; –0.78 to –0.11)	0.02
SF-36 scores, mean (SD)
PF	28 (22)	58 (25)	54 (27)	25 (28; 9.8–41)	0.008
RP	15 (31)	50 (41)	35 (45)	20 (39; –1.7 to 42)	0.07
BP	25 (26)	66 (29)	60 (34)	35 (35; 16–55)	0.006
GH	59 (22)	68 (25)	57 (21)	–2.1 (16; –11 to 6.9)	0.6
VT	33 (25)	62 (24)	54 (25)	20 (26; 4.5–35)	0.03
SF	60 (31)	80 (29)	76 (27)	16 (29; 0.034–32)	0.04
RE	60 (44)	79 (35)	84 (35)	24 (39; 3.0–46)	0.04
MH	79 (21)	87 (19)	86 (18)	7.2 (17; –2.4 to 17)	0.2