The reproductive outcome of women with hypogonadotropic hypogonadism undergoing in vitro fertilization

Figures & data

Table 1. Demographic and basal characteristics of HH and MF infertility patients.

Variables	HH (n = 33)	MF (n = 47)	p Value
Age	32.5 ± 4.73	31.3 ± 3.94	0.236
Body mass index  (kg/m^2)	26 ± 3.81	25.93 ± 4.81	0.962
FSH	0.89 ± 0.73	6.9 ± 1.52	< 0.001
LH	0.40 ± 0.51	6.4 ± 2.63	< 0.001

HH: hypogonadotropic hypogonadism; MF: male factor; FSH: follicle stimulating hormone; LH: luteinizing hormone.

Table 2. ART cycle characteristics of HH and MF infertility patients.

Variables	Hypogonadotropic hypogonadism (n = 33)	Male factor infertility (n = 47)	p Value
Duration of stimulation (day)	12.5 ± 2.06	10.08 ± 1.62	<0.001
Hcg day estradiol level (pg/ml)	2387 ± 1340	2418 ± 1034	0.909
Endometrial thickness on hcg day (mm)	10.0 ± 1.84	10.2 ± 1.89	0.559
Total gonadotropin dose used (IU)	4741 ± 1912	2157 ± 1099	<0.001
Total oocytes retrieved (n)	10.0 ± 5.8	10.7 ± 5.8	0.602
MII oocyte number (n)	8.39 ± 5.3	8.44 ± 4.42	0.962
Pregnancy rate (%)	30% (10)	31.4% (15)	0.879

ART: assisted reproductive technology; HH: hypogonadotropic hypogonadism; MF: male factor.

Table 3. Basal parameters and ART cycle characteristics in women with hypogonadotropic hypogonadism according to the oocyte number retrieved.

Variables	<5 oocytes retrieved (n = 8)	5–15 oocytes retrieved (n = 16)	>15 oocytes retrieved (n = 9)	p Value
Age (years)	34 ± 5.15	34.1 ± 4.05	28.3 ± 2.82	p = 0.004*
FSH (basal)	0.86 ± 0.95	0.92 ± 0.7	0.85 ± 0.64	p = 0.970
LH (basal)	0.37 ± 0.5	0.38 ± 0.42	0.46 ± 0.7	p = 0.919
Body mass index kg/m^2	26.5 ± 7.77	25.8 ± 2.73	26 ± 4.42	p = 0.981
Total gonadotropin dose used (IU)	5753 ± 2307	4665 ± 1943	3977 ± 1094	p = 0.158
Duration of stimulation (day)	13.2 ± 2.54	12.5 ± 2.15	10.8 ± 3.9	p = 0.193

ART: assisted reproductive technology; FSH: follicle stimulating hormone; LH: luteinizing hormone. Values are means ± standard deviation (SD). *p < 0.05 was considered significant.