Figures & data
Figure 1. Conventional and FISH cytogenetic findings. (a) A QFQ banded metaphase spread showing the supernumerary small marker chromosome (indicated). (b) FISH on metaphase spread using CEP 10 probe (white [green]), showing the both chromosomes 10, and the smaller sSMC. FISH: fluorescence in situ hybridization.
![Figure 1. Conventional and FISH cytogenetic findings. (a) A QFQ banded metaphase spread showing the supernumerary small marker chromosome (indicated). (b) FISH on metaphase spread using CEP 10 probe (white [green]), showing the both chromosomes 10, and the smaller sSMC. FISH: fluorescence in situ hybridization.](/cms/asset/2fddd0bf-3ab6-4ef5-88cf-53148dae6ec8/iaan_a_1067936_f0001_c.jpg)
Figure 2. Cytogenetic and clinical summary of patients with marker chromosome 10 described in the literature. Representation of the approximate breakpoints/genetic content of the reported sSMC(10) cases and of our case with or without clinical symptoms and with a sufficient cytogenetic characterization. Light gray (green) squares correspond to reported sSMC(10) without clinical symptoms and dark gray (red) squares to reported sSMC(10) associated with clinical findings. Breakpoints’ representation is approximated. L: lymphocytes; F: fibroblasts; NEO: neocentromere; AFC: amniotic fluid cells; CVS: chroinic villi sampling; OMC: oral mucosal cells.
