1,815
Views
21
CrossRef citations to date
0
Altmetric
Original Articles

Budesonide-loaded solid lipid nanoparticles for pulmonary delivery: preparation, optimization, and aerodynamic behavior

, , &
Pages 1964-1971 | Received 04 Jul 2015, Accepted 06 Dec 2015, Published online: 13 Jan 2016

Figures & data

Table 1. The training parameters used with INForm version 4.02 (Billingham, UK)

Table 2. The training and test data set used in ANNs modeling

Table 3. The unseen data sets utilized in ANNs modeling

Figure 1. Twin Impinger apparatus.

Figure 1. Twin Impinger apparatus.

Figure 2. 3D plots of SLNs size predicted by the ANNs model fixed at low, mid-range, and high values of the concentration.

Figure 2. 3D plots of SLNs size predicted by the ANNs model fixed at low, mid-range, and high values of the concentration.

Figure 3. 3D plots of SLNs size predicted by the ANNs model fixed at low, mid-range, and high values of the amplitude.

Figure 3. 3D plots of SLNs size predicted by the ANNs model fixed at low, mid-range, and high values of the amplitude.

Figure 4. 3D plots of SLNs size predicted by the ANNs model fixed at low, mid-range, and high values of the homogen time.

Figure 4. 3D plots of SLNs size predicted by the ANNs model fixed at low, mid-range, and high values of the homogen time.

Figure 5. SEM image of solid lipid nanoparticle.

Figure 5. SEM image of solid lipid nanoparticle.

Figure 6. The relationship between the cumulative release amount and time. Free BUDs and BUD-SLNs.

Figure 6. The relationship between the cumulative release amount and time. Free BUDs and BUD-SLNs.

Table 4. Mean (SD) for FPF results of BUD-SLNs and commercial budesonide suspension

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.