Synthesis and characterization of smart N-isopropylacrylamide-based magnetic nanocomposites containing doxorubicin anti-cancer drug

Figures & data

Figure 1. Chemical reaction for preparing (NIPAAM–DMAEMA) co-polymer.

Figure 2. DOX release from the nanocomposites.

Figure 3. FTIR spectrum of (a) (NIPAAM–DMAEMA) copolymer and (b) DOX-loaded nanocomposite.

Figure 4. ¹H-NMR spectra of poly (NIPAAM–DMAEMA).

Figure 5. Scanning electron microscopy of (a) NIPAAM–DMAEMA copolymers and (b) DOX-loaded nanocomposite.

Figure 6. Magnetic properties of (a) Fe₃O₄ nanoparticles and (b) P (NIPAAM–DMAEMA) DOX-loaded nanocomposite.

Table 1. Swelling behavior of the nanocomposites at pH and temperature

Temperature (°C)	pH	Swelling ratio
37 °C	7.4	22.3
37 °C	5.8	20.5
40 °C	7.4	8.4
40 °C	5.8	6.2