Figures & data
Figure 1. Structure of simple decision tree model. ICU = intensive care unit; RSV = respiratory syncytial virus.
![Figure 1. Structure of simple decision tree model. ICU = intensive care unit; RSV = respiratory syncytial virus.](/cms/asset/998a115a-6dae-48a2-8a3f-4a641818cb7b/ijme_a_672942_f0001_b.jpg)
Table 1. Probabilities used in the model by palivizumab prophylaxis and no prophylaxis.
Table 2. Cost of drug administration and RSV-related outcomes adjusted to 2010.
Table 3. Health utilities incorporated in the cost-effectiveness model.
Figure 2. Benchmark of palivizumab cost-effectiveness results with those of vaccines. AAP = American Academy of Pediatrics; DTaP = diptheris, tetanus, and acellular pertussis vaccine; HPV = human papillomavirus vaccine; RF = risk factor; TIV = trivalent inactivated influenza vaccine; wGA = weeks gestational age.
![Figure 2. Benchmark of palivizumab cost-effectiveness results with those of vaccines. AAP = American Academy of Pediatrics; DTaP = diptheris, tetanus, and acellular pertussis vaccine; HPV = human papillomavirus vaccine; RF = risk factor; TIV = trivalent inactivated influenza vaccine; wGA = weeks gestational age.](/cms/asset/cc2a6ca0-e0f3-4428-99af-41689b28e2c1/ijme_a_672942_f0002_b.jpg)
Table 4. Net costs and QALYS between palivizumab prophylaxis and no prophylaxis among the 4 cohorts.
Table 5. One-way sensitivity analysis for infants <32 wGA, ≤6 months CA.
Table 6. One-way for infants 32–34 wGA, ≤3 months CA with 2009 AAP RF.
Table 7. One-way for infants 32–35 wGA, ≤6 months CA with 2006 AAP RF.
Table 8. One-way sensitivity analysis for infants 32–35 wGA, ≤6 months CA with ≤1 RF.
Figures 3 and 4. Probabilistic analyses <32 wGA, ≤6 months CA. CA = chronologic age; QALY = quality-adjusted life-year; wGA = weeks gestational age.
![Figures 3 and 4. Probabilistic analyses <32 wGA, ≤6 months CA. CA = chronologic age; QALY = quality-adjusted life-year; wGA = weeks gestational age.](/cms/asset/d9de7b44-16c5-409a-bb67-e20bf3a2934b/ijme_a_672942_f0003_b.jpg)
Figures 5 and 6. Probabilistic analyses for 32–34 wGA, ≤3 months CA with AAP 2009 RF. AAP = American Academy of Pediatrics; CA = chronologic age; QALY = quality-adjusted life-year; RF = risk factor; wGA = weeks gestational age.
![Figures 5 and 6. Probabilistic analyses for 32–34 wGA, ≤3 months CA with AAP 2009 RF. AAP = American Academy of Pediatrics; CA = chronologic age; QALY = quality-adjusted life-year; RF = risk factor; wGA = weeks gestational age.](/cms/asset/8ae0f483-9c23-43b1-8b52-5c49e4e8970b/ijme_a_672942_f0004_b.jpg)
Figures 7 and 8. Probabilistic analyses 32–35 wGA, ≤6 months CA with AAP 2006 RF. AAP = American Academy of Pediatrics; CA = chronologic age; QALY = quality-adjusted life-year; RF = risk factor; wGA = weeks gestational age.
![Figures 7 and 8. Probabilistic analyses 32–35 wGA, ≤6 months CA with AAP 2006 RF. AAP = American Academy of Pediatrics; CA = chronologic age; QALY = quality-adjusted life-year; RF = risk factor; wGA = weeks gestational age.](/cms/asset/051bc764-9e67-415e-a582-6136a320d92c/ijme_a_672942_f0005_b.jpg)
Figures 9 and 10. Probabilistic analyses 32–35 wGA, ≤6 months CA with ≤1 RF. CA = chronologic age; QALY = quality-adjusted life-year; RF = risk factor; wGA = weeks gestational age.
![Figures 9 and 10. Probabilistic analyses 32–35 wGA, ≤6 months CA with ≤1 RF. CA = chronologic age; QALY = quality-adjusted life-year; RF = risk factor; wGA = weeks gestational age.](/cms/asset/211a5ed8-e1d3-4e2a-8ae1-93731c8dfb30/ijme_a_672942_f0006_b.jpg)