Age-related mild cognitive deficit: a ready-to-use concept?

Figures & data

Table I Age-related mild cognitive deficit: definitions and criteria.^10-23 AACD, aging-associated cognitive decline; AAMI, age-associated memory impairment; ACMI, age-consistent memory impairment; BVRT, Benton Visual Retention Test; CAMDEX, Cambridge Examination for Mental Disorders in the Elderly; CDR, Clinical Dementia Rating; DSM-III-R, Diagnostic and Statistical Manual of Mental Health Disorders. 3rd ed, revised; GDS, Global Deterioration Scale; HIS, Hachinski Ischemia score; HRSD, Hamilton Rating Scale for Depression; ICD-10, International Statistical Classification of Diseases and Health-related Problems. 10th revision; LLF, Late-life forgetfulness; MCI, mild cognitive impairment; MMSE, Mini-Mental State Examination; WAIS, Wechsler Adult Intelligence Scale; WMS, Wechsler Memory Scale.

Table II. Definition and criteria for mild cognitive impairment (MCI).^{21, 25-26} ADL, activities of daily living; CDR, Clinical Dementia Rating; DSM-III-R, Diagnostic and Statistical Manual of Mental Health Disorders. 3rd ed, revised; MMSE, Mini-Mental State Examination. *Although CDR score^{32, 33} was not a criterion, MCI subjects had CDR=0.5.

Figure 1. Cognitive profile in age-associated memory impairment (AAMI) and aging-associated cognitive decline (AACD) subjects, according to the data in reference 34. Memory: according to AACD criteria (at least 1 SD below age-appropriate norms). IMI, isolated memory impairment; >1 function, impairment in more than one function.

Table III. Neuropathological characteristics of mild cognitive impairment in the Religious Order Study.^43-45 CERAD, Consortium to Establish a Registry for Alzheimer's disease; MCI, mild cognitive impairment; NS, not significant; S, significant. Changes in MCI and AD group are given relative to normal controls.

Table

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