Acute and long-term treatment of mania

Figures & data

Table I The decalogue of goals for intervention in bipolar disorder.¹⁴

Table II Evidence base for the efficacy of drugs used to treat mania. Strength of evidence base (regardless of antimanic potency): +++, strong evidence (positive large placebo-controlled trials); ++, some evidence (from secondary outcomes of placebo-controlled trials or other randomized clinical trials); +, limited evidence (some evidence from small controlled studies or indirect evidence from clinical trials):?, no evidence available other than open studies; -, evidence of lack of efficacy from controlled trials.

Table III Evidence base for combinations of antipsychotics with lithium or anticonvulsants. Evidence base: +, positive in at least one placebo-controlled trial;?, no evidence available from clinical trials; -, negative results in clinical trials so far

VietaE.Managing Bipolar Disorder in Clinical Practice.London, UK: Current Medicine Group Ltd;2007

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