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Dialogues in Clinical Neuroscience Volume 12, 2010 - Issue 4

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Clinical Research

Affective neuroscience of the emotional BrainMind: evolutionary perspectives and implications for understanding depression

Neurociencias afectivas del cerebro emocional: perspectivas evolutivas y sus consecuencias para comprender la depresión

Neuroscience affective du cerveau émotionnel: perspectives évolutionistes et implications dans la compréhension de la dépression

Jaak PankseppBaily Endowed Chair for Animal Well-Being Science, Department of Veterinary & Comparative Anatomy, Pharmacology and Physiology, College of Veterinary Medicine, Washington State University Pullman, Washington, USACorrespondence[email protected]

Pages 533-545 | Published online: 01 Apr 2022

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https://doi.org/10.31887/DCNS.2010.12.4/jpanksepp

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Table I. Levels of control in brain emotion-affective processing

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Figure 1. Human and animal sadness and animal separation-distress/GRIEF systems. Animal data comes from mapping of separation distress circuits with localized electrical stimulation in guinea pigs^Citation40 and human data from PET imaging of affective states by Damasio's group.^Citation41 AC, anterior cingulate; VS, ventral striatum; dPOA, dorsal preoptic area; BN, bed nucleus of the stria terminalis; DMT, dorsomedial thalamus; PAG, periaqueductal gray

HermanBH.PankseppJ.Ascending endorphinergic inhibition of distress vocalization. Science. 1981211106010627466377

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PankseppJ.Feeling the pain of social loss. Science. 200330223723914551424

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