Applications of magnetic resonance imaging for treatment-resistant late-life depression

Figures & data

Table I Structural MRI associations with late-life depression (LLD): regional atrophy. CA, cornu ammonis; GM, gray matter; ACC, anterior cingulate cortex; WM, white matter; dLPFC, dorsolateral prefrontal cortex; OFC, orbitofrontal cortex

TABLE II Structural MRI associations with late-life depression (LLD). WMH, white matter hyperintensities.

TABLE III Structural MRI associations with late-life depression (LLD): white matter integrity. WM, white matter; DWMH, deep white matter hyperintensities; FA, fractional anisotropy; WMH, white matter hyperintensities; PCC, posterior cingulate cortex

TABLE IV Structural MRI associations with late-life depression (LLD) treatment outcomes: regional atrophy. SCID-IV-TR, Structured Clinical Interview of DSM-IV Text Revision; HDRS, Hamilton Depression Rating Scale; MADRS, Montgomery-Asberg Depression Rating Scale; GM, gray matter

TABLE V Structural MRI associations with LLD treatment outcomes: hyperintensities. HDRS, Hamilton Depression Rating Scale; SCID-IV-TR, Structured Clinical Interview of DSM-IV Text Revision; ECT, electroconvulsive therapy; MADRS, Montgomery-Asberg Depression Rating Scale; DSM-III-R, Diagnostic and Statistical Manual of Mental Disorders III; WMH, white matter hyperintensities; PVWMH, paraventricular white matter hyperintensities; DWMH, deep white matter hyperintensities; GM, gray matter; DWM, deep white matter WM, white matter; PVH, paraventricular hyperintensities

TABLE VI Structural MRI associations with late-life depression (LLD) treatment outcomes: white matter integrity. DSM-IV, Diagnostic and Statistical Manual of Mental Disorders IV; FA, functional anisotropy; dLPFC, dorsolateral prefrontal cortex; HDRS, Hamilton Depression Rating Scale; AC, anterior commissure; PC, posterior commissure; MADRS, Montgomery-Asberg Depression Rating Scale

TABLE VII Functional MRI associations with late-life depression (LLD): resting-state fMRI. FC, functional connectivity; CCN, cognitive control network; DMN, default mode network

TABLE VIII Functional MRI associations with late-life depression (LLD): task-based fMRI. dACC, dorsal anterior cingulate cortex; dLPFC, dorsolateral prefrontal cortex; FC, functional connectivity; dACC, dorsal anterior cingulate cortex; PCC, posterior cingulate cortex; LLD, late-life depression; BA, Brodmann area

TABLE IX Functional MRI associations with late-life depression (LLD) treatment outcomes: resting-state fMRI. MADRS, Montgomery-Asberg Depression Rating Scale; DSM-IV, Diagnostic and Statistical Manual of Mental Disorders IV; FC, functional connectivity; CCN, cognitive control network; HDRS, Hamilton Depression Rating Scale; PCC, posterior cingulate cortex; PFC, prefrontal cortex; ACC, anterior cingulate cortex;

TABLE X Functional MRI associations with late-life depression (LLD) treatment outcomes: task-based fMRI. HDRS, Hamilton Depression Rating Scale; dLPFC, dorsolateral prefrontal cortex; vmPFC, ventromedial prefrontal cortex

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