Vacuum-assisted closure versus conventional dressings in the management of diabetic foot ulcers: a prospective case–control study

Figures & data

Table 1 Safety and efficacy of VAC over conventional dressings in the treatment of diabetic foot ulcers

Patient characteristics	Cases	Controls	*p
Age (mean±SD years)	53.79±5.45	54.57±4.78	0.569
100% granulation (N)	27	25	0.049
Week 4 (%)	18 (66.7%)	7 (28%)
Week 5	3 (11.1%)	3 (12%)
Week 6	2 (7.4%)	2 (8%)
Week 7	0	3 (12%)
Week 8	0	2 (8%)
Never during treatment	4 (14.8%)	8 (32%)
Disappearance of wound discharge			0.0001
Week 2	2 (7.4%)	0 (0.0%)
Week 3	4 (14.8%)	0
Week 4	12 (44.4%)	0
Week 5	3 (11.1%)	4 (16%)
Week 6	1 (3.7%)	5 (20%)
Week 7	3 (11%)	9 (36%)
Week 8	2 (7.4%)	7 (28%)
Blood culture positivity	10 (35.7%)	14 (50%)	0.187
Change in wound size^†
Decrease	22 (78.6%)	15 (53.6%)
No change	5 (17.9%)	10 (35.7%)
Increase	1 (3.6%)	3 (10.7)
Need for amputation	1 (3.6%)	3 (10.7)	0.299
Spontaneous wound closure	3 (13.6%)	1 (6.67%)	0.503
Endpoint reached			0.048
Yes	22 (78.6%)	15 (53.6%)
No	6 (21.4%)	13 (46.4%)
Patient satisfaction
Excellent	22 (78.6%)	3 (10.7%)	0.00
Very good	0	3 (10.7%)	0.00
Good	0	9 (32.1%)	0.00
Not satisfied			0.00

*Chi-square test; ^†measured as length (cm)×width (cm).