Restoring large-scale brain networks in PTSD and related disorders: a proposal for neuroscientifically-informed treatment interventions

Figures & data

Fig. 1 Neuroscientifically-informed treatment interventions in psychotraumatology: Three intrinsic networks, including the central executive network (CEN), salience network (SN), and default mode network (DMN) may be associated with specific clinical symptoms observed in PTSD, including cognitive dysfunction (CEN), hyper- and hypoarousal/interoception (SN), and an altered sense of self (DMN). Specific testable treatment interventions targeted to restore each one of these brain networks and related clinical dysfunction are suggested. Images were created using network templates available from http://findlab.stanford.edu/functional_ROIs.html (Shirer, Ryali, Rykhlevskaia, Menon, & Greicius, 2012).

Shirer W. R., Ryali S., Rykhlevskaia E., Menon V., Greicius M. D. Decoding subject-driven cognitive states with whole-brain connectivity patterns. Cerebral Cortex. 2012; 22(1): 158–165. [PubMed Abstract] [PubMed CentralFull Text] 10.1093/cercor/bhr099.

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