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Original Articles

Absorption, excretion, and retention of selenium from a high selenium yeast in men with a high intake of selenium

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Article: 1642 | Received 04 Oct 2007, Published online: 12 Feb 2008

Figures & data

Table 1. Characteristics of the 12 human male volunteers at baseline

Figure 1.  Mean tracer in urine from the single 77Se dose detectable before administration (day 0) of a single oral dose and at day 1, 2, 3, and 14 after tracer administration (Mean±SD; Day 0 to 3: n = 12; Day 14: n = 6).

Figure 2.  Mean tracer in faeces from the single 77Se dose as percentage of the total selenium detectable before marker excretion (day 0) and in samples of day 1 – 3, 4 – 5, and day 14 after tracer excretion. The periods were pooled according to the markers taken simultaneous with the single dose. The data are presented as mean values±SD with 12 specimens at day 0 and day 1–3. The data of day 4–5 and day 14 included 9 and 6 specimens, respectively.

Figure 3.  Mean plasma 77Se tracer concentration (µg/L) in 12 human volunteers given a single oral dose of 327 µg 77Se as Selenium yeast together with a light meal after an overnight fast (Mean±SD; n = 12).

Table 2. Intake, absorption, excretion and retention of 327 µg 77Se administered as a single dose to 12 men with a habitual high intake of Se. The values are based on urinary and faecal excretion from days 1–3 after administration of 77Se. Values are given as median values with 10–90% percentiles and also as means±standard deviation. Values are further given as % of the ingested dose with 10–90% percentiles and also±standard deviation.