A two-year clinical lifestyle intervention program for weight loss in obesity

Figures & data

Table 1. Clinical lifestyle intervention program protocol.

Visit	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15
Week	1–2*	5	8	14	20	26	32**	38	44	50	56	68	80	92	104
Weight recording	X	X	X	X	X	X	X	X	X	X	X	X	X	X	X
SAD recording	X						X								X
Biochemical control	X						X								X
Physician	X						X
Dietician	X	X		X		X***	X		X		X***		X		X
Nurse	X		X				X	X				X		X
Physiotherapist	X				X		X			X
Almoner	X

*Two weeks (80 h) introductory education at the outpatient clinic.

**Two days (16 h) rehearsal at the outpatient clinic.

***Two hours follow-up visit including dietician supervised cooking.

Table 2. Baseline characteristics of patients completing the lifestyle intervention program.

Characteristics	Females	Males
Number	100	26
Age (years)	48±12	50±10
Body weight (kg)	103.5±18.1	116.5±22.5
Body mass index (kg/m^2)	37.6±6.2	36.5±5.3
Sagital diameter (cm)	29.0±2.9	31.5±3.8
Total cholesterol (mmol/l)	5.6±1.0	5.5±1.2
HDL-cholesterol (mmol/l)	1.3±0.3	1.2±0.2
Triglycerides (mmol/l)	2.3±1.2	3.7±4.5
Blood glucose (mmol/l)	5.7±1.7	7.0±3.4
SBP (mmHg)	126±16	131±17
DBP (mmHg)	76±9	82±12
Diabetes type 2 (n (%))	20 (20)	9 (35)
Hypertension (n (%))	15 (15)	7 (27)

Data presented are arithmetic means±standard deviations, number or percent.

Figure 1.  Frequency of participants obtaining weight loss ≥5%. The black bars present percentage of participants losing ≥5 but <10%. The white bars present percentage of participants losing >/10%.

Table 3. Metabolic variables at 32 and 104 weeks in the lifestyle intervention program and percent changes from baseline in program completers.

	32 weeks				104 weeks
	Female		Male		Female		Male
Variable	Mean±SD	n	Mean±SD	n	Mean±SD	n	Mean±SD	N
Body weight (kg)	98.5±17.9***	80	105.4±21.1***	24	99.7±18.3***	100	112.1±22.7*	26
Change (%)	–6.5±6.0***		–8.2±8.1***		–3.5±7.4***		–3.7±7.1*
BMI (kg/m^2)	35.7±6.2***	80	33.6±4.9***	24	36.2±6.3***	100	34.7±4.5*	24
Change (%)	–6.5±6.0***		–8.2±8.1***		–3.5±7.4***		–3.7±7.1*
SAD (cm)	–		–		27.6±3.5***	84	30.0±4.0**	18
Change (%)	–		–		–5.4±8.0***		–4.8±6.8**
Total cholesterol (mmol/l)	5.5±1.1	92	5.2±1.2	21	5.5±1.1	94	5.6±1.0	21
Change (%)	–1.3±13.4		–0.6±16.5		–0.9±16.0		1.0±17.4
Triglycerides (mmol/l)	1.9±1.2***	92	1.8±0.9	21	1.8±1.1***	93	2.2±1.0***	21
Change (%)	–15.8±31.3***		–22.8±22.4		–16.1±33.4***		–24.2±24.6***
Blood glucose (mmol/l)	5.2±1.2***	92	5.1±1.4*	21	5.8±1.9	92	6.6±3.1	20
Change (%)	–6.2±18.0***		–16.1±18.0*		2.6±20.2		–5.9±20.3
Systolic blood pressure	–		–		129±16	86	135±15	19
Change (%)	–		–		2.3±6.2**		3.0±8.2*
Diastolic blood pressure	–		–		79±8	86	84±9	19
Change (%)	–		–		3.9±9.7**		2.4±6.5

*p<0.05, **p<0.01, ***p<0.001, p-values were determined by Student's paired t-test for differences from baseline.