Homocysteine as a potential biochemical marker for depression in elderly stroke survivors

Figures & data

Table 1. Age, Montgomery Åsberg Depression Rating Scale (MADRS) scores, homocysteine (tHcy) and methylmalonic acid (MMA) in stroke survivors

	N	Mean (SE)	Median
Female	97
Age		82 (0.55)	83.08
MADRS		11.40 (0.90)	9
tHcy	79	12.24 (0.64)	11
MMA	78	0.27 (0.01)	0.25
Male	52
Age		79.23 (0.64)	78.99
MADRS		8.23 (0.90)	7
tHcy	39	12.05 (0.69)	11
MMA	38	0.24 (0.01)	0.23

>15 µmol/L = cut off point of tHcy.>0.37 µmol/L = cut off point of serum MMA. Higher MADRS scores represent more depressive symptomatology. Means, Medians and SE Including Age, Gender, tHcy Expression and MADRS Scores, Presented by Gender.

Table 2. Coefficients, standard error of the coefficients and standardised beta values of the regression model

	B	SE B	β	R2
Step 1				0.03
Constant	12.42	12.42
Age	−0.13	0.15	−0.08
Gender	−3.08	1.63	−0.18
Step 2				0.06
Constant	12.08	12.26
Age	−0.05	0.15	−0.03
Gender	−3.13	1.61	−0.18
tHcy	0.28	0.14	0.18*

Note: R2 = 0.03 for Step 1: ΔR2 = 0 .06 for Step 2 (p<0.05).

*Significant at p < 0.05.