Prostate cancer in Germany among migrants from the Former Soviet Union

Figures & data

Fig. 1.  Age-standardised prostate cancer mortality rates per 100,000 (Segi Standard).

Table 1. Descriptive results of both migrant cohorts, from North-Rhine Westphalia and Saarland

	Migrant cohort in the Federal State of NRW	Migrant cohort in the Federal State of Saarland
Number of cohort members	34,393	18,619
Males (%)	16,734 (48.7%)	8,977 (48.2%)
Females (%)	17,659 (51.3%)	9,642 (51.8%)
Immigration period	1990–2001	1990–2005
1990–1993	14,728	6,933
1994–1997	11,441	6,536
1998–2001/5	8,224	5,150
Age restriction	15 +	-
Mean age at migration
(standard deviation; range)	40.0 (17.0; 15–97)	32.4 (19.8; 0–103)
Males	38.4 (16.0; 15–93)	30.9 (19.0; 0–95)
Females	41.5 (17.7; 15–97)	33.8 (20.4; 0–103)
End of follow up date	31-12-2005	31-12-2005
Mean duration of follow up	10.1 years	8.0 years
Person-years	346,671.5	148,313.1
Males	167,882.0	71703.4
Females	178,789.4	76,609.6
Alive	89.2%	73.2%
Dead	7.5%	4.2%
Lost to follow up	3.3%	22.6%
Prostate cancer Incident cases	–	35
Deaths	24	4

Fig. 2.  Overview of all 35 incident prostate cancer cases from the Saarland cohort sorted by age at diagnosis.

Table 2. Standardised incidence and mortality ratios of the migrant cohorts in comparison to the German resp. state of Saarland population

	Observed	Expected	SIR/SMR (95% CI)
Incidence (Saarland cohort)	35	47.3	0.74 (0.52–1.03)
Mortality (both cohorts)	28	48.7	0.57 (0.38–0.83)

Table 3. Poisson regression analysis on prostate cancer incidence in comparison to the German population, state of Saarland

Model	Variable(s).	Deviance	Difference of deviance^*	df	p model	β	p β
0	(Null model)	269.5	–	–	–
1.1	Calendar year	265.3	4.2	1	0.04	–0.09	0.04
1.2	Years since immigration	268.5	1.0	1	0.31	–0.05	0.31
1.3	Age	266.6	2.9	1	0.09	–0.17	0.08
1.4	Age dichotomized (<60 vs. 60 + )	265.9	4.6	1	0.03	–0.83	0.04
2.1	Calendar year + Age	262.2	7.3	2	0.03	–0.09	0.03
						–0.18	0.07
2.2						–0.09	0.03
	Calendar year + Age (<60 vs. 60 + )	261.6	7.9	2	0.02
						–0.84	0.04
3.1						–0.06	0.67
	Calendar year + age+(calendar year)×(age)	262.1	7.4	3	0.06	–0.16
						–0.01	0.75
						–0.11	0.01
	Calendar year + age(<60 vs. 60 + )+					–0.55	0.30
3.2	(calendar year)×(age (<60 vs. 60 + ))	260.5	9.0	3	0.03	–0.11	0.31

Relative to null model