Journal of Extracellular Vesicles
Volume 4, 2015 - Issue 1
Open access
66,044
Views
3,351
CrossRef citations to date
0
Altmetric
Review Articles
Biological properties of extracellular vesicles and their physiological functions
María Yáñez-MóUnidad de Investigación, Hospital Sta Cristina, Instituto de Investigaciones Sanitarias Princesa (IIS-IP), Madrid, Spain;Departamento de Biología Molecular, UAM, Madrid, SpainCorrespondence[email protected] [email protected] [email protected]
, Pia R.-M. SiljanderExtracellular Vesicle Research, Division of Biochemistry and Biotechnology, Department of Biosciences, University of Helsinki, Helsinki, Finland;Division of Pharmaceutical Biosciences, Faculty of Pharmacy, University of Helsinki, Helsinki, FinlandCorrespondence[email protected] [email protected] [email protected]
, Zoraida AndreuUnidad de Investigación, Hospital Sta Cristina, Instituto de Investigaciones Sanitarias Princesa (IIS-IP), Madrid, Spain;Departamento de Biología Molecular, UAM, Madrid, Spain
, Apolonija Bedina ZavecLaboratory for Molecular Biology and Nanobiotechnology, National Institute of Chemistry, Ljubljana, Slovenia
, Francesc E. BorràsIVECAT Group – “Germans Trias i Pujol” Research Institute, Badalona, Spain;Nephrology Service – “Germans Trias i Pujol” University Hospital, Badalona, Spain
, Edit I. BuzasDepartment of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary
, Krisztina BuzasBiological Research Centre, Hungarian Academy of Sciences, Szeged, Hungary;Faculty of Dentistry, University of Szeged, SzegedHungary
, Enriqueta CasalMetabolomics Unit, CIC bioGUNE, CIBERehd, Bizkaia Technology Park, Derio, Spain
, Francesco CappelloDepartment of Experimental Biomedicine and Clinical Neuroscience, Human Anatomy Section, University of Palermo, Palermo, Italy;Euro-Mediterranean Institute of Science and Technology, Palermo, Italy
, Joana CarvalhoInstituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal;Expression Regulation in Cancer, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal
, Eva ColásResearch Unit in Biomedicine and Translational Oncology, Vall Hebron Institute of Research and Autonomous University of Barcelona, Barcelona, Spain
, Anabela Cordeiro-da SilvaInstituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal;IBMC – Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal;Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Porto, Portugal
, Stefano FaisAnti-Tumour Drugs Section, Department of Therapeutic Research and Medicines Evaluation, National Institute of Health (ISS), Rome, Italy
, Juan M. Falcon-PerezMetabolomics Unit, CIC bioGUNE, CIBERehd, Bizkaia Technology Park, Derio, Spain;IKERBASQUE, Basque Foundation for Science, Bilbao, Spain
, Irene M. GhobrialDana-Farber Cancer Institute, Boston, MA, USA
, Bernd GiebelInstitute for Transfusion Medicine, University Hospital Essen, University of Duisburg-Essen, Essen, Germany
, Mario GimonaSpinal Cord Injury & Tissue Regeneration Center Salzburg (SCI-TReCS), Paracelsus Medical University (PMU), Salzburg, Austria;Department of Blood Group Serology and Transfusion Medicine, Universitätsklinikum, Salzburger Landeskliniken GesmbH (SALK), Salzburg, Austria
, Michael GranerDepartment of Neurosurgery, University of Colorado Denver, CO, USA
, Ihsan GurselDepartment of Molecular Biology and Genetics Thorlab-Therapeutic Oligonucleotide Research Lab, Bilkent University, Ankara, Turkey
, Mayda GurselDepartment of Biological Sciences Middle East Technical University, Ankara, Turkey
, Niels H. H. HeegaardDepartment of Clinical Biochemistry and Pharmacology, Odense University Hospital, University of Southern Denmark, Odense, Denmark;Analytical Protein Chemistry, Department of Clinical Biochemistry, Immunology & Genetics, Statens Serum Institut, Copenhagen, Denmark
, An HendrixLaboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University Hospital, Ghent, Belgium
, Peter KierulfBood Cell Research Group, Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway
, Katsutoshi KokubunDana-Farber Cancer Institute, Boston, MA, USA
, Maja KosanovicDepartment of Immunochemistry and Glycobiology, Institute for the Application of Nuclear Energy, INEP, University of Belgrade, Belgrade, Serbia
, Veronika Kralj-IglicLaboratory of Clinical Biophysics, Faculty of Health Sciences, University of Ljubljana, Ljubljana, Slovenia
, Eva-Maria Krämer-AlbersMolecular Cell Biology and Focus Program Translational Neurosciences, University of Mainz, Mainz, Germany
, Saara LaitinenResearch and Cell Services, Finnish Red Cross Blood Service, Helsinki, Finland
, Cecilia LässerKrefting Research Centre, Institute of Medicine at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
, Thomas LenerSpinal Cord Injury & Tissue Regeneration Center Salzburg (SCI-TReCS), Paracelsus Medical University (PMU), Salzburg, Austria;Department of Blood Group Serology and Transfusion Medicine, Universitätsklinikum, Salzburger Landeskliniken GesmbH (SALK), Salzburg, Austria
, Erzsébet LigetiDepartment of Physiology, Semmelweis University, Budapest, Hungary
, Aija LinēLatvian Biomedical Research and Study Centre, Riga, Latvia
, Georg LippsInstitute of Chemistry and Bioanalytics, School of Life Sciences, University of Applied Sciences and Arts Northwestern Switzerland, Muttenz, Switzerland
, Alicia LlorenteDepartment of Molecular Cell Biology, Institute for Cancer Research, Oslo University Hospital – The Norwegian Radium Hospital, Oslo, Norway
, Jan LötvallKrefting Research Centre, Institute of Medicine at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
, Mateja Manček-KeberNational Institute of Chemistry, Laboratory of Biotechnology, Ljubljana, Slovenia;EN→FIST Centre of Excellence, Ljubljana, Slovenia
, Antonio MarcillaDepartamento de Biología Celular y Parasitologia, Facultat de Farmacia, Universitat de Valencia, Valencia, Spain
, Maria MittelbrunnDepartment of Vascular Biology and Inflammation, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain
, Irina NazarenkoInstitute for Environmental Health Sciences and Hospital Infection Control Medical Center – University of Freiburg, Freiburg im Breisgau, Germany
, Esther N.M. Nolte-‘t HoenDepartment of Biochemistry and Cell Biology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
, Tuula A. NymanInstitute of Biotechnology, (Viikinkaari 1), University of Helsinki, Helsinki, Finland
, Lorraine O'DriscollSchool of Pharmacy and Pharmaceutical Sciences & Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland
, Mireia OlivanResearch Unit in Biomedicine and Translational Oncology, Vall Hebron Institute of Research and Autonomous University of Barcelona, Barcelona, Spain
, Carla OliveiraInstituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal;Expression Regulation in Cancer, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal;Department of Pathology and Oncology, Faculty of Medicine, University of Porto, Porto, Portugal
, Éva PállingerDepartment of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary
, Hernando A. del PortilloISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic – Universitat de Barcelona, Barcelona, Spain;Institució Catalana de Recerca I Estudis Avançats, Barcelona, Spain
, Jaume ReventósResearch Unit in Biomedicine and Translational Oncology, Vall Hebron Institute of Research and Autonomous University of Barcelona, Barcelona, Spain;Departament de Ciències Bàsiques, Universitat Internacional de Catalunya, and Institut de Recerca Biomèdica de Bellvitge, Barcelona, Spain
, Marina RigauResearch Unit in Biomedicine and Translational Oncology, Vall Hebron Institute of Research and Autonomous University of Barcelona, Barcelona, Spain
, Eva RohdeSpinal Cord Injury & Tissue Regeneration Center Salzburg (SCI-TReCS), Paracelsus Medical University (PMU), Salzburg, Austria;Department of Blood Group Serology and Transfusion Medicine, Universitätsklinikum, Salzburger Landeskliniken GesmbH (SALK), Salzburg, Austria
, Marei SammarDepartment of Biotechnology Engineering, ORT Braude College, Karmiel, Israel
, Francisco Sánchez-MadridDepartment of Vascular Biology and Inflammation, Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain;Servicio de Inmunología, Hospital de la Princesa, Instituto de Investigaciones Sanitarias Princesa (IIS-IP), Madrid, Spain
, N. SantarémInstituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal;IBMC – Instituto de Biologia Molecular e Celular, Universidade do Porto, Porto, Portugal
, Katharina SchallmoserSpinal Cord Injury & Tissue Regeneration Center Salzburg (SCI-TReCS), Paracelsus Medical University (PMU), Salzburg, Austria;Department of Blood Group Serology and Transfusion Medicine, Universitätsklinikum, Salzburger Landeskliniken GesmbH (SALK), Salzburg, Austria
, Marie Stampe OstenfeldDepartmnet of Molecular Medicine, Aarhus University Hospital, Aarhus, Denmark
, Willem StoorvogelDepartment of Biochemistry and Cell Biology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
, Roman StukeljLaboratory of Clinical Biophysics, Faculty of Health Sciences, University of Ljubljana, Ljubljana, Slovenia
, Susanne G. Van der GreinDepartment of Biochemistry and Cell Biology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
, M. Helena VasconcelosInstituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal;Cancer Drug Resistance Group, Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal;Department of Biological Sciences, Faculty of Pharmacy, University of Porto (FFUP), Porto, Portugal
, Marca H. M. WaubenDepartment of Biochemistry and Cell Biology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
& Olivier De WeverLaboratory of Experimental Cancer Research, Department of Radiation Oncology and Experimental Cancer Research, Ghent University Hospital, Ghent, Belgium
show all
Article: 27066
|
Received 22 Dec 2014, Accepted 03 Oct 2015, Published online: 14 May 2015
Related Research Data
Microvesicles from cancer cell lines
Source:
Wiley
Detailed analysis of the plasma extracellular vesicle proteome after separation from lipoproteins
Source:
Springer Science and Business Media LLC
Leukocyte extracellular vesicle concentration is inversely associated with liver fibrosis severity in NAFLD.
Source:
Wiley
Total Extracellular Small RNA Profiles from Plasma, Saliva, and Urine of Healthy Subjects.
Source:
Nature Publishing Group
Lymphatic exosomes promote dendritic cell migration along guidance cues.
Source:
Rockefeller Univ. Press
Molecular interactions at the surface of extracellular vesicles
Source:
Springer Science and Business Media LLC
Mesenchymal Stem Cells-Derived Exosomes for Wound Regeneration.
Source:
Springer International Publishing
Extracellular vesicles and chronic inflammation during HIV infection
Source:
Taylor & Francis Group
Markers of endothelial damage in patients with chronic kidney disease on hemodialysis.
Source:
American Physiological Society
Qualitative differences in T‐cell activation by dendritic cell‐derived extracellular vesicle subtypes
Source:
HAL CCSD
Second trimester extracellular microRNAs in maternal blood and fetal growth: An exploratory study
Source:
Informa UK Limited
A Comparative Study of Serum Exosome Isolation Using Differential Ultracentrifugation and Three Commercial Reagents
Source:
Public Library of Science (PLoS)
The Complement System: A Prey of Trypanosoma cruzi
Source:
Frontiers Media SA
Proteomic and histopathological characterisation of sicca subjects and primary Sjögren's syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers.
Source:
Springer Science and Business Media LLC
Magnetic Silica-Coated Iron Oxide Nanochains as Photothermal Agents, Disrupting the Extracellular Matrix, and Eradicating Cancer Cells.
Source:
HAL CCSD
Dendritic cells and routing cargo into exosomes.
Source:
Wiley
Tetraspanin-decorated extracellular vesicle-mimetics as a novel adaptable reference material.
Source:
Taylor & Francis Group
Extracellular vesicles induce minimal hepatotoxicity and immunogenicity.
Source:
Royal Society of Chemistry (RSC)
Detection of long non-coding RNAs in human breastmilk extracellular vesicles: Implications for early child development
Source:
Informa UK Limited
The impact of circulating preeclampsia-associated extracellular vesicles on the migratory activity and phenotype of THP-1 monocytic cells.
Source:
Springer Science and Business Media LLC
Metabolomics Applied to the Study of Extracellular Vesicles
Source:
MDPI AG
SOD1 in Amyotrophic Lateral Sclerosis: “Ambivalent” Behavior Connected to the Disease
Source:
MDPI AG
Lipidomic profiling of extracellular vesicles derived from prostate and prostate cancer cell lines.
Source:
BMC
Extracellular Vesicles from Vascular Endothelial Cells Promote Survival, Proliferation and Motility of Oligodendrocyte Precursor Cells.
Source:
Public Library of Science (PLoS)
Monocytes mediate homing of circulating microvesicles to the pulmonary vasculature during low-grade systemic inflammation.
Source:
Taylor & Francis Group
Progress in Microfluidics-Based Exosome Separation and Detection Technologies for Diagnostic Applications.
Source:
Wiley
Strategies for the use of Extracellular Vesicles for the Delivery of Therapeutics.
Source:
Springer Science and Business Media LLC
Extracellular vesicles – biogenesis, composition, function, uptake and therapeutic applications
Source:
Walter de Gruyter GmbH
Silencing of carbonic anhydrase I enhances the malignant potential of exosomes secreted by prostatic tumour cells.
Source:
Wiley
Glycosylation of extracellular vesicles: current knowledge, tools and clinical perspectives
Source:
Informa UK Limited
Exosomes Released from Rabies Virus-Infected Cells May be Involved in the Infection Process.
Source:
Springer Science and Business Media LLC
Latest advances in extracellular vesicles: from bench to bedside
Source:
Informa UK Limited
Cancer Immunotherapy Based on Natural Killer Cells: Current Progress and New Opportunities
Source:
Frontiers Media S.A.
Small RNA trafficking at the forefront of plant-pathogen interactions.
Source:
F1000 Research Ltd
Therapeutic effects of adipose-tissue-derived mesenchymal stromal cells and their extracellular vesicles in experimental silicosis.
Source:
Springer Science and Business Media LLC
Molecular Mechanisms of Breast Cancer Metastasis to the Lung: Clinical and Experimental Perspectives
Source:
MDPI AG
Extracellular Vesicles as Drug Delivery Vehicles to the Central Nervous System
Source:
Springer Science and Business Media LLC
BRAIN-DERIVED EXTRACELLULAR VESICLES ARE HIGHLY ENRICHED IN THE PRION PROTEIN AND ITS C1 FRAGMENT: RELEVANCE FOR CELLULAR UPTAKE AND IMPLICATIONS IN STROKE
Source:
Cold Spring Harbor Laboratory
Proteomic profiling of extracellular vesicles allows for human breast cancer subtyping
Source:
Nature Publishing Group
Extracellular Vesicles in Brain Tumors and Neurodegenerative Diseases.
Source:
Frontiers Media S.A.
Long non-coding RNAs in hematological malignancies: translating basic techniques into diagnostic and therapeutic strategies.
Source:
Springer Science and Business Media LLC
microRNA in Cardiovascular Aging and Age-Related Cardiovascular Diseases
Source:
Frontiers Media S.A.
Small RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers.
Source:
Informa UK Limited
Chapter 5 Curvature-Induced Sorting of Bilayer Membrane Constituents and Formation of Membrane Rafts
Source:
Elsevier
Vesicular and Extra-Vesicular RNAs of Human Blood Plasma.
Source:
Springer International Publishing
Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies
Source:
Nature Publishing Group
Matrix-bound nanovesicles within ECM bioscaffolds.
Source:
American Association for the Advancement of Science (AAAS)
Endocrine Crosstalk Between Skeletal Muscle and the Brain.
Source:
Frontiers Media SA
Optimization of small RNA library preparation protocol from human urinary exosomes
Source:
Springer Science and Business Media LLC
Quantitative changes in the protein and miRNA cargo of plasma exosome-like vesicles after exposure to ionizing radiation.
Source:
Informa UK Limited
Assessment of methods for serum extracellular vesicle small RNA sequencing to support biomarker development.
Source:
Informa UK Limited
Oligodendrocytes support axonal transport and maintenance via exosome secretion
Source:
Cold Spring Harbor Laboratory
Prostate cancer cells and exosomes in acidic condition show increased carbonic anhydrase IX expression and activity
Source:
Taylor & Francis
Isolation and Detection Technologies of Extracellular Vesicles and Application on Cancer Diagnostic.
Source:
SAGE Publications
Melanoma Affects the Composition of Blood Cell-Derived Extracellular Vesicles
Source:
Frontiers Media SA
Circulating exosomal microRNAs reveal the mechanism of Fructus Meliae Toosendan-induced liver injury in mice.
Source:
Springer Science and Business Media LLC
Leukocyte-Derived Extracellular Vesicles in Blood with and without EpCAM Enrichment
Source:
Multidisciplinary Digital Publishing Institute
Preliminary Characterization of Extracellular Vesicles From Auditory HEI-OC1 Cells.
Source:
eScholarship, University of California
Extracellular Vesicles as Carriers of Non-coding RNAs in Liver Diseases.
Source:
Frontiers Media SA
Arbelaiz et al.
Source:
Wiley
Toll-Like Receptors 2 and 4 Modulate Pulmonary Inflammation and Host Factors Mediated by Outer Membrane Vesicles Derived from Acinetobacter baumannii.
Source:
American Society for Microbiology
Exosome-mediated horizontal gene transfer occurs in double-strand break repair during genome editing
Source:
Springer Science and Business Media LLC
Exosomes and cardiovascular cell-cell communication.
Source:
Portland Press Ltd.
Stem cell-derived extracellular vesicles attenuate the early inflammatory response after tendon injury and repair.
Source:
Wiley
Towards Therapeutic Delivery of Extracellular Vesicles: Strategies for In Vivo Tracking and Biodistribution Analysis
Source:
Hindawi Limited
Salivary Biomarkers for Oral Squamous Cell Carcinoma Diagnosis and Follow-Up: Current Status and Perspectives.
Source:
Frontiers Media SA
Extracellular vesicles in cancer immune responses: roles of purinergic receptors.
Source:
Springer Science and Business Media LLC
Extracellular microRNAs in follicular fluid and their potential association with oocyte fertilization and embryo quality: an exploratory study
Source:
Springer Science and Business Media LLC
Variety of RNAs in Peripheral Blood Cells, Plasma, and Plasma Fractions
Source:
Hindawi Limited
Wnt Signaling in Renal Cell Carcinoma
Source:
MDPI AG
Three dimensions of structural complexity of HLA-G
Source:
Wiley
Senescent Microvesicles: A Novel Advance in Molecular Mechanisms of Atherosclerotic Calcification
Source:
MDPI AG
Endosomal escape enhancing compounds facilitate functional delivery of extracellular vesicle cargo.
Source:
Future Medicine Ltd
The Complex Interplay Between Extracellular Matrix and Cells in Tissues.
Source:
Springer New York
Human bone marrow mesenchymal stem/stromal cell behaviour is coordinated via mechanically activated osteocyte-derived extracellular vesicles
Source:
Cold Spring Harbor Laboratory
Endothelial Extracellular Vesicles-Promises and Challenges
Source:
Frontiers Media SA
Secretome of Mesenchymal Stem Cells and Its Potential Protective Effects on Brain Pathologies.
Source:
Springer Science and Business Media LLC
New Insights Into the Long Non-coding RNA SRA: Physiological Functions and Mechanisms of Action.
Source:
Frontiers Media SA
Serum extracellular vesicle depletion processes affect release and infectivity of HIV-1 in culture.
Source:
Nature Portfolio
Human induced pluripotent stem cell–derived extracellular vesicles reduce hepatic stellate cell activation and liver fibrosis
Source:
American Society for Clinical Investigation
High-throughput sequencing of two populations of extracellular vesicles provides an mRNA signature that can be detected in the circulation of breast cancer patients.
Source:
eScholarship, University of California
Role of Microvesicles in the Spread of Herpes Simplex Virus 1 in Oligodendrocytic Cells.
Source:
American Society for Microbiology
Extracellular RNA in aging
Source:
Wiley
Microvesicles Released from Human Red Blood Cells: Properties and Potential Applications
Source:
InTech
Atherosclerotic Conditions Promote the Packaging of Functional MicroRNA-92a-3p Into Endothelial Microvesicles
Source:
Ovid Technologies (Wolters Kluwer Health)
Contribution of Extracellular Vesicles in Rebuilding Injured Muscles.
Source:
Frontiers Media S.A.
An Update on in Vivo Imaging of Extracellular Vesicles as Drug Delivery Vehicles.
Source:
Frontiers Media SA
Extracellular Vesicles From Sporothrix brasiliensis Are an Important Virulence Factor That Induce an Increase in Fungal Burden in Experimental Sporotrichosis.
Source:
Frontiers Media S.A.
Adipose-Derived Mesenchymal Stem Cells Promote M2 Macrophage Phenotype through Exosomes
Source:
Hindawi Limited
Lipidomic characterization of extracellular vesicles in human serum.
Source:
SAGE Publications
GMSC-Derived Exosomes Combined with a Chitosan/Silk Hydrogel Sponge Accelerates Wound Healing in a Diabetic Rat Skin Defect Model.
Source:
Frontiers Media S.A.
Preeclampsia and Extracellular Vesicles
Source:
Springer Science and Business Media LLC
Exosome markers associated with immune activation and oxidative stress in HIV patients on antiretroviral therapy
Source:
Nature Portfolio
Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication.
Source:
HAL CCSD
Ambient particulate matter and microRNAs in extracellular vesicles: a pilot study of older individuals
Source:
BioMed Central
Cellular senescence contributes to age-dependent changes in circulating extracellular vesicle cargo and function.
Source:
Wiley
Exosomes and microvesicles in normal physiology, pathophysiology, and renal diseases
Source:
Springer Science and Business Media LLC
Identification of small RNAs in extracellular vesicles from the commensal yeast Malassezia sympodialis.
Source:
Nature Publishing Group
Biological roles and potential applications of immune cell-derived extracellular vesicles.
Source:
Informa UK Limited
Role of exosomes in the protection of cellular homeostasis
Source:
Informa UK Limited
A preliminary investigation of circulating extracellular vesicles and biomarker discovery associated with treatment response in head and neck squamous cell carcinoma
Source:
Springer Science and Business Media LLC
The importance of the vascular endothelial barrier in the immune-inflammatory response induced by radiotherapy.
Source:
HAL CCSD
Cross Talk between Adipose Tissue and Placenta in Obese and Gestational Diabetes Mellitus Pregnancies via Exosomes
Source:
Frontiers Research Foundation
Endocrine Resistance in Hormone Receptor Positive Breast Cancer-From Mechanism to Therapy.
Source:
Frontiers Media SA
Fluorescence labelling of extracellular vesicles using a novel thiol-based strategy for quantitative analysis of cellular delivery and intracellular traffic
Source:
Royal Society of Chemistry (RSC)
Cholangiocyte-derived exosomal long noncoding RNA H19 promotes cholestatic liver injury in mouse and humans.
Source:
Wiley
The role of exosome in autoimmune connective tissue disease.
Source:
Informa UK Limited
Increases in miR-124-3p in Microglial Exosomes Confer Neuroprotective Effects by Targeting FIP200-Mediated Neuronal Autophagy Following Traumatic Brain Injury.
Source:
Springer Science and Business Media LLC
Cortactin promotes exosome secretion by controlling branched actin dynamics.
Source:
Rockefeller University Press
EV-associated miRNAs from peritoneal lavage as potential diagnostic biomarkers in colorectal cancer
Source:
BioMed Central
Exosomes for repair, regeneration and rejuvenation.
Source:
Informa Healthcare
Post-translational add-ons mark the path in exosomal protein sorting.
Source:
Springer Science and Business Media LLC
Quantum Dot Based Nano-Biosensors for Detection of Circulating Cell Free miRNAs in Lung Carcinogenesis: From Biology to Clinical Translation.
Source:
Frontiers Media S.A.
α2-HS Glycoprotein in Plasma Extracellular Vesicles Inhibits the Osteogenic Differentiation of Human Mesenchymal Stromal Cells In Vitro.
Source:
Hindawi Limited
The biological functions and clinical applications of exosomes in lung cancer
Source:
Springer Science and Business Media LLC
Precipitation with polyethylene glycol followed by washing and pelleting by ultracentrifugation enriches extracellular vesicles from tissue culture supernatants in small and large scales.
Source:
Informa UK Limited
A simple fluorescence aptasensor for gastric cancer exosome detection based on branched rolling circle amplification
Source:
Royal Society of Chemistry (RSC)
Human Mesenchymal Stem Cell (hMSC) -Derived Exosomes/Exosome Mimetics as a Potential Novel Therapeutic Tool for Regenerative Medicine
Source:
Springer Singapore
Metabolic alterations in urine extracellular vesicles are associated to prostate cancer pathogenesis and progression.
Source:
Informa UK Limited
Application of Microfluidic Chips in Separation and Analysis of Extracellular Vesicles in Liquid Biopsy for Cancer
Source:
MDPI AG
Human neutrophils produce antifungal extracellular vesicles against Aspergillus fumigatus
Source:
American Society for Microbiology
Elucidating diversity of exosomes: biophysical and molecular characterization methods.
Source:
Future Medicine Ltd
Urinary proteomics and metabolomics studies to monitor bladder health and urological diseases
Source:
Springer Nature
Exosomes derived from oviduct cells mediate the EGFR/MAPK signaling pathway in cumulus cells.
Source:
Wiley
Extracellular vesicles in diabetes mellitus induce alterations in endothelial cell morphology and migration.
Source:
Springer Science and Business Media LLC
Organ crosstalk: the potent roles of inflammation and fibrotic changes in the course of organ interactions.
Source:
Springer Science and Business Media LLC
Triple negative breast cancer-derived microvesicles transfer microRNA221 to the recipient cells and thereby promote epithelial-to-mesenchymal transition
Source:
American Society for Biochemistry & Molecular Biology (ASBMB)
Interaction of Extracellular Vesicles with Si Surface Studied by Nanomechanical Microcantilever Sensors
Source:
MDPI AG
Tissue factor activity on microvesicles from cancer patients.
Source:
Springer Science and Business Media LLC
The potential of endurance exercise-derived exosomes to treat metabolic diseases
Source:
Springer Science and Business Media LLC
Exosomes as Mediators of the Systemic Adaptations to Endurance Exercise
Source:
Cold Spring Harbor Laboratory
Metabolomic Profile of Oviductal Extracellular Vesicles across the Estrous Cycle in Cattle.
Source:
MDPI AG
Small RNAs detected in exosomes derived from the MH7A synovial fibroblast cell line with TNF-α stimulation.
Source:
Public Library of Science (PLoS)
Clinical translation of myocardial conditioning
Source:
American Physiological Society
Blister fluid exosomes in bullous pemphigoid
Source:
Wiley
Protocol for Exosome Isolation from Small Volume of Ovarian Follicular Fluid: Evaluation of Ultracentrifugation and Commercial Kits.
Source:
Springer New York
Pitfalls associated with lipophilic fluorophore staining of extracellular vesicles for uptake studies.
Source:
Taylor & Francis Group
Exosomal lipid composition and the role of ether lipids and phosphoinositides in exosome biology
Source:
American Society for Biochemistry & Molecular Biology (ASBMB)
Extracellular Vesicles from Hypoxic Adipocytes and Obese Subjects Reduce Insulin-Stimulated Glucose Uptake
Source:
Wiley-VCH Verlag
Serum-Derived Extracellular Vesicles from African Swine Fever Virus-Infected Pigs Selectively Recruit Viral and Porcine Proteins
Source:
MDPI AG
Elevated exosomal lysyl oxidase like 2 is a potential biomarker for head and neck squamous cell carcinoma.
Source:
Wiley
Cardiovascular morbidities of obstructive sleep apnea and the role of circulating extracellular vesicles.
Source:
SAGE Publishing
Extracellular Vesicles Released by Human Induced-Pluripotent Stem Cell-Derived Cardiomyocytes Promote Angiogenesis.
Source:
Frontiers Media SA
Emerging Role of Genetic Alterations Affecting Exosome Biology in Neurodegenerative Diseases.
Source:
Molecular Diversity Preservation International (MDPI)
The emerging clinical potential of circulating extracellular vesicles for non-invasive glioma diagnosis and disease monitoring.
Source:
Springer Science and Business Media LLC
Extracellular Vesicles Shedding Promotes Melanoma Growth in Response to Chemotherapy.
Source:
Nature Publishing Group
Extracellular Vesicles Carry HIV Env and Facilitate Hiv Infection of Human Lymphoid Tissue
Source:
Springer Science and Business Media LLC
Extracellular vesicles in bone: "dogrobbers" in the "eternal battle field".
Source:
Springer Science and Business Media LLC
Extracellular vesicles in human semen modulate antigen-presenting cell function and decrease downstream antiviral T cell responses.
Source:
Public Library of Science (PLoS)
The Role of Microparticles as Biomarkers in the Development of Therapy for Autoimmune Disease
Source:
Springer International Publishing
Association of Extracellular Vesicle Protein Cargo with Race and Clinical Markers of Mortality
Source:
Springer Science and Business Media LLC
Modification of the glycosylation of extracellular vesicles alters their biodistribution in mice.
Source:
Zenodo
Imaging flow cytometry facilitates multiparametric characterization of extracellular vesicles in malignant brain tumours
Source:
Taylor & Francis Group
Exosome labeling by lipophilic dye PKH26 results in significant increase in vesicle size
Source:
bioRxiv
Extracellular nanovesicles released from the commensal yeast Malassezia sympodialis are enriched in allergens and interact with cells in human skin
Source:
Springer Science and Business Media LLC
Host- and Microbiota-Derived Extracellular Vesicles, Immune Function, and Disease Development
Source:
MDPI AG
Extracellular vesicles with altered tetraspanin CD9 and CD151 levels confer increased prostate cell motility and invasion.
Source:
Springer Science and Business Media LLC
Role of Extracellular Vesicles and microRNAs on Dysfunctional Angiogenesis during Preeclamptic Pregnancies.
Source:
Frontiers Media SA
Surface glycans contribute to differences between seminal prostasomes from normozoospermic and oligozoospermic men.
Source:
Informa UK Limited
ExtraPEG: A Polyethylene Glycol-Based Method for Enrichment of Extracellular Vesicles.
Source:
Springer Science and Business Media LLC
Circulating CD3+HLA-DR+ Extracellular Vesicles as a Marker for Th1/Tc1-Type Immune Responses
Source:
Hindawi
From Inflammasome to Exosome-Does Extracellular Vesicle Secretion Constitute an Inflammasome-Dependent Immune Response?
Source:
Frontiers Media SA
Некодирующие РНК в диагностике пневмонии
Source:
Cardiology Research Institute
Extracellular vesicle isolation methods: rising impact of size-exclusion chromatography
Source:
Springer Science and Business Media LLC
Assessing the role of surface glycans of extracellular vesicles on cellular uptake.
Source:
Springer Science and Business Media LLC
Circulating exosomes measure responses to therapy in head and neck cancer patients treated with cetuximab, ipilimumab, and IMRT.
Source:
Informa UK Limited
Metabolic signature of extracellular vesicles depends on the cell culture conditions.
Source:
Informa UK Limited
Potential Applications in Diagnosis, Prognosis, and Epidemiology
Source:
Ovid Technologies (Wolters Kluwer Health)
In vivo characterisation of endogenous cardiovascular extracellular vesicles in larval and adult zebrafish
Source:
Cold Spring Harbor Laboratory
Microvesicles released during the interaction between Trypanosoma cruzi TcI and TcII strains and host blood cells inhibit complement system and increase the infectivity of metacyclic forms of host cells in a strain-independent process.
Source:
Oxford University Press (OUP)
Alcohol Exposure Impacts the Composition of HeLa-Derived Extracellular Vesicles.
Source:
Multidisciplinary Digital Publishing Institute
Innate immunity to malaria-The role of monocytes.
Source:
Wiley
Recent Progress in Isolation and Detection of Extracellular Vesicles for Cancer Diagnostics.
Source:
Wiley
Tumorigenesis, diagnosis, and therapeutic potential of exosomes in liver cancer
Source:
Springer Science and Business Media LLC
Tumor-Derived Extracellular Vesicles Inhibit Natural Killer Cell Function in Pancreatic Cancer
Source:
MDPI AG
Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells
Source:
Springer Science and Business Media LLC
Current knowledge on exosome biogenesis and release
Source:
Springer Science and Business Media LLC
Potential role of microRNAs in mammalian female fertility.
Source:
CSIRO Publishing
Proteomic analysis reveals procoagulant properties of cigarette smoke-induced extracellular vesicles
Source:
Informa UK Limited
MSC surface markers (CD44, CD73, and CD90) can identify human MSC-derived extracellular vesicles by conventional flow cytometry
Source:
Springer Science and Business Media LLC
Damage-associated molecular patterns in trauma.
Source:
Springer Science and Business Media LLC
Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes.
Source:
HAL CCSD
Current understanding of the therapeutic benefits of mesenchymal stem cells in acute respiratory distress syndrome.
Source:
Springer Science and Business Media LLC
Extracellular Vesicles: Intercellular Mediators in Alcohol-Induced Pathologies
Source:
Springer Science and Business Media LLC
Antibody-Based Assays for Phenotyping of Extracellular Vesicles
Source:
Hindawi Limited
Understanding extracellular vesicle diversity - current status
Source:
Informa UK Limited
A Promising Biocompatible Platform: Lipid-Based and Bio-Inspired Smart Drug Delivery Systems for Cancer Therapy.
Source:
MDPI AG
Role of retinal pigment epithelium-derived exosomes and autophagy in new blood vessel formation.
Source:
Wiley
Curvature-dependent lateral distribution of raft markers in the human erythrocyte membrane
Source:
Informa UK Limited
QUORUM SENSING: Cell-to-Cell Communication in Bacteria
Source:
Annual Reviews
Monitoring the dynamics of cell-derived extracellular vesicles at the nanoscale by liquid-cell transmission electron microscopy
Source:
Royal Society of Chemistry (RSC)
Protein-Based Salivary Profiles as Novel Biomarkers for Oral Diseases.
Source:
Hindawi Limited
Extracellular vesicles in renal disease
Source:
Springer Science and Business Media LLC
Stem cell-derived extracellular vesicles inhibit and revert fibrosis progression in a mouse model of diabetic nephropathy
Source:
Springer Science and Business Media LLC
The role of extracellular vesicles in biomineralisation: current perspective and application in regenerative medicine.
Source:
SAGE Publications
LSPR detection of extracellular vesicles using a silver-PDMS nano-composite platform suitable for sensor networks
Source:
Informa UK Limited
Elevated levels of extracellular vesicles are associated with therapy failure and disease progression in breast cancer patients undergoing neoadjuvant chemotherapy.
Source:
Taylor & Francis Group
miR-22-5p and miR-29a-5p Are Reliable Reference Genes for Analyzing Extracellular Vesicle-Associated miRNAs in Adipose-Derived Mesenchymal Stem Cells and Are Stable under Inflammatory Priming Mimicking Osteoarthritis Condition
Source:
Springer Science and Business Media LLC
The current state and future directions of RNAi-based therapeutics.
Source:
Springer Science and Business Media LLC
Milk’s Role as an Epigenetic Regulator in Health and Disease
Source:
Universität Regensburg
The Diagnostic and Prognostic Potential of microRNAs in Epithelial Ovarian Carcinoma
Source:
Springer Science and Business Media LLC
Extracellular Vesicle MicroRNA Transfer in Lung Diseases.
Source:
Frontiers Media SA
Oncogenic H-Ras Expression Induces Fatty Acid Profile Changes in Human Fibroblasts and Extracellular Vesicles
Source:
MDPI AG
Flow cytometric analysis of extracellular vesicle subsets in plasma: impact of swarm by particles of non-interest.
Source:
Wiley
Extracellular vesicles as trans‐genomic agents: Emerging roles in disease and evolution
Source:
Wiley
Microenvironmental pH and Exosome Levels Interplay in Human Cancer Cell Lines of Different Histotypes.
Source:
MDPI AG
The potential diagnostic and prognostic role of extracellular vesicles in glioma: current status and future perspectives.
Source:
Taylor & Francis
A new role for extracellular vesicles: how small vesicles can feed tumors' big appetite.
Source:
Elsevier
Detection and Quantification of Extracellular Vesicles via FACS: Membrane Labeling Matters!
Source:
MDPI AG
Systems biology approaches to investigating the roles of extracellular vesicles in human diseases.
Source:
Springer Science and Business Media LLC
Extracellular vesicles and their content in bioactive lipid mediators: more than a sack of microRNA.
Source:
American Society for Biochemistry & Molecular Biology (ASBMB)
Circulating Cancer Stem Cell-Derived Extracellular Vesicles as a Novel Biomarker for Clinical Outcome Evaluation.
Source:
Apollo - University of Cambridge Repository
Cancer extracellular vesicles contribute to stromal heterogeneity by inducing chemokines in cancer-associated fibroblasts
Source:
Springer Science and Business Media LLC
Mesenchymal stromal cell-derived extracellular vesicles: regenerative and immunomodulatory effects and potential applications in sepsis
Source:
Springer Science and Business Media LLC
A review of studies of the proteomes of circulating microparticles: key roles for galectin-3-binding protein-expressing microparticles in vascular diseases and systemic lupus erythematosus.
Source:
Springer Nature
Characterization of an umbilical cord blood sourced product suitable for allogeneic applications.
Source:
Future Medicine Ltd
The Emerging Roles of Extracellular Vesicles As Communication Vehicles within the Tumor Microenvironment and Beyond.
Source:
Frontiers Media SA
Therapeutic biomaterials based on extracellular vesicles: classification of bio-engineering and mimetic preparation routes.
Source:
Informa UK Limited
Multifaceted Mechanisms of Vascular Calcification in Aging.
Source:
Ovid Technologies (Wolters Kluwer Health)
Antigen B from Echinococcus granulosus enters mammalian cells by endocytic pathways
Source:
Public Library of Science (PLoS)
Isolation of Extracellular Vesicles by Ultracentrifugation.
Source:
Springer New York
Biocompatibility of highly purified bovine milk-derived extracellular vesicles.
Source:
Taylor & Francis Group
Interaction with hyaluronan matrix and miRNA cargo as contributors for in vitro potential of mesenchymal stem cell-derived extracellular vesicles in a model of human osteoarthritic synoviocytes
Source:
Springer Science and Business Media LLC
Extracellular vesicles in urologic malignancies-Implementations for future cancer care.
Source:
Wiley
Exosomes in tuberculosis: Still terra incognita?
Source:
Wiley
Functionalized DNA Enables Programming Exosomes/Vesicles for Tumor Imaging and Therapy.
Source:
Wiley
Endothelial Extracellular Vesicles Produced by Senescent Cells: Pathophysiological Role in the Cardiovascular Disease Associated with all Types of Diabetes Mellitus.
Source:
Bentham Science Publishers Ltd.
A bead-assisted flow cytometry method for the semi-quantitative analysis of Extracellular Vesicles.
Source:
Springer Science and Business Media LLC
Circulating microRNAs as minimal residual disease biomarkers in childhood acute lymphoblastic leukemia.
Source:
Springer Science and Business Media LLC
Detection and Characterization of Extracellular Vesicles by Transmission and Cryo-Transmission Electron Microscopy.
Source:
Springer New York
Enrichment of extracellular vesicles from tissues of the central nervous system by PROSPR
Source:
Springer Nature
Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles
Source:
HAL CCSD
An improved 96 well plate format lipid quantification assay for standardisation of experiments with extracellular vesicles
Source:
Informa UK Limited
Microparticles as biomarkers of venous thromboembolic events
Source:
Future Medicine Ltd
Kaposi sarcoma-associated herpesvirus infection in HIV patients: potential role of HIV-associated extracellular vesicles
Source:
bioRxiv
Dietary Na+ intake in healthy humans changes the urine extracellular vesicle prostasin abundance while the vesicle excretion rate, NCC, and ENaC are not altered.
Source:
American Physiological Society
Extracellular vesicles in ovarian cancer: applications to tumor biology, immunotherapy and biomarker discovery
Source:
Informa UK Limited
Hepatology Communications
Source:
Wiley
Advances in Technologies for Purification and Enrichment of Extracellular Vesicles.
Source:
SAGE Publications
Hsp60 as a Novel Target in IBD Management: A Prospect.
Source:
Frontiers Media SA
Lactobacillus casei BL23 Produces Microvesicles Carrying Proteins That Have Been Associated with Its Probiotic Effect
Source:
Frontiers Media SA
TEM ExosomeAnalyzer: a computer-assisted software tool for quantitative evaluation of extracellular vesicles in transmission electron microscopy images.
Source:
Informa UK Limited
Plasma lipidome reveals critical illness and recovery from human Ebola virus disease
Source:
Proceedings of the National Academy of Sciences
Dictyostelium: A Model for Studying the Extracellular Vesicle Messengers Involved in Human Health and Disease.
Source:
HAL CCSD
Potential Role of Exosomes in Cancer Metastasis.
Source:
Hindawi Limited
Extracellular Vesicle Biology in Alzheimer’s Disease and Related Tauopathy
Source:
Springer Science and Business Media LLC
Membrane-associated gamma-glutamyl transferase and alkaline phosphatase in the context of concanavalin A- and wheat germ agglutinin-reactive glycans mark seminal prostasome populations from normozoospermic and oligozoospermic men.
Source:
Upsala Medical Society
Clinical Application of Mesenchymal Stem Cell-Derived Extracellular Vesicle-Based Therapeutics for Inflammatory Lung Diseases.
Source:
MDPI AG
Dewetting-induced formation and mechanical properties of synthetic bacterial outer membrane models (GUVs) with controlled inner-leaflet lipid composition
Source:
Royal Society of Chemistry (RSC)
The Missing Link: How Exosomes and miRNAs can Help in Bridging Psychiatry and Molecular Biology in the Context of Depression, Bipolar Disorder and Schizophrenia.
Source:
Springer Science and Business Media LLC
Dietary bovine milk exosomes elicit changes in bacterial communities in C57BL/6 mice.
Source:
American Physiological Society
Fourier Transform Infrared Spectroscopy as a Cancer Screening and Diagnostic Tool: A Review and Prospects.
Source:
MDPI AG
Overview of Extracellular Vesicles, Their Origin, Composition, Purpose, and Methods for Exosome Isolation and Analysis
Source:
MDPI AG
Membrane-encapsulated camouflaged nanomedicines in drug delivery.
Source:
Future Medicine Ltd
Exosomes derived from HIV-1-infected cells promote growth and progression of cancer via HIV TAR RNA
Source:
Springer Science and Business Media LLC
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.