Figure 1. Docking of PtdIns3P into binding site 1 (A) and 2 (B) of K. lactis Hsv2. (C) Docking studies suggest binding of PROPPINs perpendicular to the membrane. Note that parts of the protein are predicted to insert into the membrane. The phosphates of the phospholipids are shown in orange; their polar groups in violet. The shaded bar depicts the hydrophobic part of the membrane. Only the upper membrane leaflet is shown. The figures are adopted from Krick et al. PNAS 109:E2042.
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